Goiter
MONDO:0005397Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing.
Also known as: Thyromegaly, goiter, goiter (disease), goitre (disease)
102 clinical trials for this condition and its sub-types, 12 tagged with Goiter itself.
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Sub-types of Goiter
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Toxic diffuse goiter 0 trials · 53 incl. sub-types
1 sub-type
- Graves disease 53 trials Sub-types →
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Nodular goiter 36 trials · 43 incl. sub-types
1 sub-type
- Multinodular goiter 10 trials Sub-types →
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Endemic goiter 4 trials
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Nontoxic goiter 1 trial
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Substernal goiter 1 trial
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Dyshormonogenic goiter 0 trials
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Lingual goiter 0 trials
Most studied deeper sub-types
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Electric pulses zap thyroid lumps in new trial
Disease control Recruiting nowThis study tests a new device that uses electrical pulses to shrink benign (non-cancerous) thyroid nodules. About 100 adults with symptomatic nodules will receive the treatment and be followed to see if the nodule shrinks and symptoms improve. The goal is to offer a less invasive…
Sponsor: Pulse Biosciences, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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UK doctors trial tiny particle blockage to shrink thyroid lumps
Disease control Recruiting nowThis pilot study will test the safety of thyroid artery embolization (TAE) in 10 UK patients with benign thyroid nodules or goitre. TAE is a minimally invasive procedure that blocks blood flow to the thyroid gland using tiny particles, causing it to shrink. The goal is to see if …
Sponsor: Royal Berkshire NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New hope for goiter sufferers: blocking blood flow to nodules may ease breathing trouble
Symptom relief Recruiting nowThis study is testing a procedure called thyroid artery embolization (TAE) for people with large thyroid nodules that press on the throat or windpipe, causing symptoms like trouble swallowing or breathing. The procedure blocks blood flow to the nodules to shrink them. Researchers…
Sponsor: Université de Sherbrooke • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Neck nerve block may ease Body's stress during thyroid surgery
Knowledge-focused Recruiting nowThis study tests whether a nerve block in the neck, given during thyroid surgery, can lower the body's stress response. 48 adults will be split into two groups: one gets standard anesthesia, the other gets the same plus a nerve block. Researchers will measure stress markers in bl…
Phase 4 • Sponsor: University Hospital Dubrava • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New questionnaire aims to track throat discomfort after thyroid surgery
Knowledge-focused Recruiting nowThis study aims to create a reliable questionnaire to measure swallowing and throat discomfort in people with goiter or after thyroid removal (thyroidectomy). Researchers will interview patients to develop the questions, then test the questionnaire before and after surgery. The s…
Sponsor: Istituto Auxologico Italiano • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC