Glaucoma
MONDO:0005041Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.
Also known as: glaucoma, glaucoma (disease)
332 clinical trials for this condition and its sub-types, 217 tagged with Glaucoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Glaucoma
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Open-angle glaucoma 185 trials · 192 incl. sub-types
7 sub-types
- Low tension glaucoma 21 trials
- Juvenile open angle glaucoma 7 trials · 15 incl. sub-types Sub-types →
- OPTN-related open angle glaucoma 0 trials
- Glaucoma 1, open angle, O 0 trials
- Glaucoma 1, open angle, P 0 trials
- Glaucoma type 1C 0 trials
- Residual stage of open angle glaucoma 0 trials
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Hereditary glaucoma 0 trials · 49 incl. sub-types
12 sub-types
- Exfoliation syndrome 32 trials
- Juvenile open angle glaucoma 7 trials · 15 incl. sub-types Sub-types →
- Congenital glaucoma 6 trials · 7 incl. sub-types Sub-types →
- Anterior segment dysgenesis 3 1 trial
- Iris hypoplasia with glaucoma 1 trial
- OPTN-related open angle glaucoma 0 trials
- TEK-related primary glaucoma 0 trials Sub-types →
- Glaucoma 1, open angle, O 0 trials
- Glaucoma 1, open angle, P 0 trials
- Glaucoma secondary to spherophakia/ectopia lentis and megalocornea 0 trials
- Glaucoma with elevated episcleral venous pressure 0 trials
- Hereditary glaucoma, primary closed-angle 0 trials
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Phacogenic glaucoma 0 trials · 33 incl. sub-types
2 sub-types
- Exfoliation syndrome 32 trials
- Phacolytic glaucoma 1 trial
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Angle-closure glaucoma 15 trials · 27 incl. sub-types
2 sub-types
- Primary angle-closure glaucoma 14 trials · 18 incl. sub-types Sub-types →
- Neovascular glaucoma 7 trials
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Borderline glaucoma 5 trials
2 sub-types
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Steroid-induced glaucoma 2 trials
1 sub-type
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Secondary early-onset glaucoma 1 trial
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Traumatic glaucoma 1 trial
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Aqueous misdirection 0 trials
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Glaucomatous atrophy of optic disk 0 trials
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Hypersecretion glaucoma 0 trials
Most studied deeper sub-types
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Glaucoma device Follow-Up study ends early
Disease control Stopped earlyThis study looked at the long-term safety and effectiveness of the STREAMLINE® Surgical System in people with open-angle glaucoma. It included 17 patients who had already taken part in an earlier trial of the same device. The goal was to see if the device continued to safely lowe…
Sponsor: New World Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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VR headsets tested as a possible treatment for blindness
Disease control Stopped earlyThis study tested whether using a virtual reality headset for one-hour sessions could help regenerate damaged optic nerves and improve vision in people with glaucoma or other retinal diseases. The idea came from promising results in rodents. However, the trial was terminated earl…
Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Glaucoma Drug-Eluting contact lens trial halted after single patient
Disease control Stopped earlyThis study tested a special contact lens that slowly releases the glaucoma drug latanoprost, aiming to replace daily eye drops. Only one person enrolled before the study was stopped early. The goal was to check safety and whether the lens could lower eye pressure, but no conclusi…
Phase 1 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Portable devices could take the guesswork out of eye pressure checks
Diagnosis Stopped earlyEye pressure is usually measured with a technique called Goldmann applanation tonometry, which doctors consider the gold standard but which depends on the examiner's skill and offers limited repeatability. Researchers at Duke University are testing automated versions of this meas…
Sponsor: Duke University • Aim: Diagnosis
Last updated Sep 13, 2026 00:00 UTC
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Tiny drops, big hope? study tests nanodropper for glaucoma
Symptom relief Stopped earlyThis study tested whether a device called Nanodropper, which makes smaller eye drops, works as well as standard eye drops for lowering eye pressure in people with glaucoma or ocular hypertension. The study enrolled 16 adults who already used a common glaucoma drop. The goal was t…
Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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New gel aims to soothe dry eyes in glaucoma patients
Symptom relief Stopped earlyThis study looked at whether a preservative-free eye gel called IRIDIUM® could help relieve dry eye symptoms in people with glaucoma or high eye pressure who were already using multiple eye drop medications. The goal was to see if the gel improved comfort and quality of life. The…
Sponsor: Fidia Farmaceutici s.p.a. • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Glaucoma patients test vision from home in new study
Knowledge-focused Stopped earlyThis study looked at whether people with glaucoma would keep doing vision tests at home on an iPad every two weeks for six months. Eight patients took part. The goal was to see how often they tested and if the home test could catch worsening vision. Researchers also asked patient…
Sponsor: Andrew Pouw, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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New EyeCheck device put to the test for glaucoma monitoring
Knowledge-focused Stopped earlyThis study aimed to see if a new device called the EyeCheck monitor can measure eye pressure as accurately as standard tools in people with glaucoma or suspected glaucoma. Twenty-two participants used the device during a clinic visit. The study was stopped early, so results are l…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New eye camera could spot hidden signs of blindness
Knowledge-focused Stopped earlyThis study tested a new, non-invasive eye imaging method called hyperspectral imaging. It takes pictures of the back of the eye using many different colors of light to find details not visible with standard cameras. About 679 adults with healthy eyes or eye diseases like diabetic…
Sponsor: Center for Eye Research Australia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Glaucoma screening study halted after only 26 participants
Knowledge-focused Stopped earlyThis study aimed to collect eye scan data from people with and without glaucoma to develop a new screening tool called the Topcon Health Score. The researchers planned to use a special camera to measure the thickness of nerve layers in the eye. However, the study was terminated e…
Sponsor: Topcon Corporation • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:52 UTC