Food allergy

Researchers test whether daily oral immunotherapy can safely treat food allergy in children aged 0 to 2 with peanut, tree nut, or sesame allergy. Half the children receive the therapy, starting with tiny amounts of the allergen and building up over about six months, then a year o…

Researchers are testing an experimental injectable drug called LP-003 in people with wheat allergy that triggers allergic reactions during exercise. The Phase II trial enrolls 12 participants aged 12 to 60 who have a history of wheat or gluten allergy and react to a small amount …

This trial tests whether a four-step ladder made with goat milk formula helps children aged 1 to 5 with cow's milk allergy build tolerance to milk better than the standard cow's milk ladder. Both ladders start with baked goods and progress to plain milk over 12 weeks, with each s…

This trial is testing an investigational drug called LP-003, a type of antibody that may block allergic responses. The goal is to see if it can increase the amount of peanut protein that people with peanut allergy can eat without having allergic symptoms. The study involves about…

This trial tests whether giving children with cow's milk allergy tiny, increasing amounts of milk each day can help them tolerate it. Infants aged 6 to 18 months with a confirmed allergy will be randomly assigned to receive oral immunotherapy for 1-1.5 years or to avoid milk as u…

This trial tests whether giving children with allergies to multiple nuts a daily oral immunotherapy—a mix of peanut, cashew, walnut, hazelnut, and almond proteins—can help them tolerate these foods. Children aged 1-12 with confirmed allergies to at least two of these nuts are ran…

This study tests if giving children with egg allergy a tiny amount of egg every day (oral immunotherapy) helps them outgrow the allergy faster. About 40 children will take part, and each year they will be tested to see if they are still allergic. The goal is to compare how quickl…

This study tests a treatment called sublingual immunotherapy (SLIT) for children ages 1-11 with cashew allergy. For 18 months, children receive daily drops under the tongue to see if they can safely eat more cashew without a reaction. The goal is to reduce allergy severity, not c…

This Phase 2 trial tests two forms of peanut oral immunotherapy in 57 people aged 4 to 30 with peanut allergy. One group gets standard blanched peanut protein, the other gets autoclaved (high-pressure heated) peanut protein, both in gradually increasing doses. The goal is to see …

This study follows 39 children with cashew allergy who previously received oral immunotherapy (OIT) with cashew protein. After 8 more months of OIT, they will stop treatment for 4 weeks and then take a food challenge to see if they can safely eat cashews without ongoing therapy. …

This trial evaluates whether a blood test called Flow CAST® can accurately identify peanut allergy. Researchers will compare results from people with peanut allergy, people with other allergies, and healthy controls. The goal is to see if this test can reliably distinguish those …

This study tests whether AI-powered decision trees can help general practitioners better diagnose and manage allergies. About 600 patients with suspected allergies will be enrolled, and doctors will use an app that suggests next steps based on symptoms. The goal is to see if this…

This study tests whether a special package of bathing, skincare, and allergen exposure advice can prevent food allergies in infants at risk. Researchers will compare the package to usual care in 64 newborns. Parents will follow recommendations like delaying the first bath and avo…

Researchers at a French hospital are following 100 children aged 6 months to 17 years who are allergic to legumes other than peanut, such as peas, chickpeas, lentils, soy, lupin, and fava beans. The study tracks which legumes cause reactions, how old children are at first symptom…

This study follows 120 children and adolescents in Spain who have been newly diagnosed with IgE-mediated fish allergy. Researchers will collect data on symptoms, test results, and molecular sensitization patterns to better understand how fish allergy presents in this population. …

This study will test 35 people with known or suspected allergies to cannabis, tree nuts, or seeds to see if they are also allergic to hemp seeds. Participants will receive skin prick tests and blood tests to measure allergic reactions. The goal is to understand the potential alle…

This study looks at how different ways of processing soy (like heating or fermenting) change its ability to cause allergic reactions. Researchers will test processed soy in the lab and then on the skin of 55 adults with soy allergy. The goal is to understand which processing meth…