Fontan-associated liver disease
MONDO:0979326Chronic disease that occur as a complication of the Fontan procedure, a palliative surgery for patients with congenital heart disease that results in a single-ventricle circulation.
5 clinical trials for this condition and its sub-types, 5 tagged with Fontan-associated liver disease itself.
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New test could spot liver trouble early in fontan patients
Knowledge-focused Recruiting nowThis study is testing a new way to measure liver function in adults who have had the Fontan procedure, a surgery for certain heart defects. Researchers will use a dual cholate clearance test (a special blood test) and a heart MRI to see how well the liver is working. They will co…
Sponsor: HepQuant, LLC • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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New study seeks clues to liver damage after fontan surgery
Knowledge-focused Recruiting nowThis study looks at why some adults who had the Fontan procedure as children develop serious liver scarring. Researchers will use blood tests, imaging, and liver biopsies to track changes and find early markers of disease. The goal is to better understand the process and pave the…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Heart drug dosing study aims to protect fontan Patients' livers
Knowledge-focused Recruiting nowThis study looks at how liver congestion and scarring affect the way the body processes two common drugs, sildenafil and pravastatin, in people with Fontan circulation. Researchers will give a single dose of each drug to 15 participants aged 8 and older and measure drug levels in…
Phase 1 • Sponsor: Children's Mercy Hospital Kansas City • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC