Fibrous dysplasia

MONDO:0000845

A genetic, non-inheritable disorder caused by osteoblastic differentiation defects that result in the replacement of bone marrow and trabecular bone by fibrous stroma and immature bone. It usually affects a single bone and less frequently multiple bones. Skull, femur, tibia, and humerus are the most frequently affected bones. It manifests with pain, deformities, and fractures.

Also known as: fibrous dysplasia of bone

11 clinical trials for this condition and its sub-types, 11 tagged with Fibrous dysplasia itself.

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Where it sits in the disease tree

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Part of

↑ Bone remodeling disease (413)

Sub-types of Fibrous dysplasia

Including sub-types (11) Tagged with Fibrous dysplasia (11)

Trials to join now! 3 Not yet finished but already full! 1 Completed 7

New computer model aims to predict fractures in rare bone disorder patients

Knowledge-focused Ongoing

This study is testing whether a computer tool called MEKANOS can better predict the risk of hip fractures in people with Fibrous Dysplasia or McCune-Albright Syndrome. Researchers will take CT scans of the femur and use the tool to calculate bone strength. The goal is to improve …

Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused

Last updated Jun 27, 2026 12:03 UTC

Fibrous dysplasia

Where it sits in the disease tree

New computer model aims to predict fractures in rare bone disorder patients