Fatal familial insomnia
MONDO:0010808Fatal familial insomnia (FFI) is a very rare form of prion disease characterized by subacute onset of insomnia showing as a reduced overall sleep time, autonomic dysfunction, and motor disturbances.
Also known as: fatal familial insomnia, FFI, Insomnia familial fatal, Insomnia, fatal familial, familial fatal insomnia, fatal familial INSOMNIA
28 clinical trials for this condition and its sub-types, 4 tagged with Fatal familial insomnia itself.
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A sip for better sleep? beverage put to the test
Symptom relief Not yet recruitingThis trial tests whether a concentrated beverage taken daily for 28 days can improve sleep quality in adults aged 18 to 60 with mild sleep issues. Participants keep sleep diaries and complete questionnaires on sleep quality and fatigue. The study uses a single-arm design, meaning…
Sponsor: Sirio Pharma Co., Ltd • Aim: Symptom relief
Last updated Jul 26, 2026 00:00 UTC
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Can a narcolepsy drug fix ICU sleep problems?
Symptom relief Not yet recruitingThis study tests whether a drug called gamma-hydroxybutyrate (GHB) can help intensive care patients get better deep sleep. Sleep problems are very common in the ICU and can lead to serious issues like confusion and longer recovery. The trial will give GHB or a placebo to 24 adult…
Phase 2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Can a bedtime pill fix sleep troubles in kids with anorexia?
Symptom relief Not yet recruitingThis study tests a slow-release melatonin (PedPRM) in 120 children aged 6 to 18 who have anorexia nervosa and trouble sleeping. Participants take either melatonin or a placebo for 13 weeks. The goal is to see if it safely improves total sleep time and related symptoms like anxiet…
Phase 3 • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC