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Extensively drug-resistant tuberculosis
MONDO:0100482A type of drug-resistant tuberculosis that is resistant to any fluoroquinolone, and at least one of three second-line injectable drugs (capreomycin, kanamycin, and amikacin), in addition to resistance to rifampicin and isoniazid.
Also known as: XDR-TB
11 clinical trials for this condition and its sub-types, 5 tagged with Extensively drug-resistant tuberculosis itself.
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Can a new TB vaccine protect children with HIV?
Vaccine CancelledThis trial is testing two tuberculosis (TB) vaccines—VPM1002 and a repeat BCG vaccination—in pre-adolescents aged 8-14 who were vaccinated at birth. The goal is to see if these vaccines are safe and trigger a strong immune response in children both with and without HIV, and in th…
Phase 1/2 • Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group • Aim: Vaccine
Last updated Aug 19, 2026 00:00 UTC
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New hope for kids with Drug-Resistant TB: bedaquiline trial launches
Disease control PausedThis study tests a drug called bedaquiline in children and teens (0 months to under 18 years) with multidrug-resistant tuberculosis (MDR-TB), a lung infection that does not respond to standard antibiotics. About 60 participants will receive bedaquiline along with other TB medicat…
Phase 2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC