Extensively drug-resistant tuberculosis

MONDO:0100482

A type of drug-resistant tuberculosis that is resistant to any fluoroquinolone, and at least one of three second-line injectable drugs (capreomycin, kanamycin, and amikacin), in addition to resistance to rifampicin and isoniazid.

Also known as: XDR-TB

11 clinical trials for this condition and its sub-types, 5 tagged with Extensively drug-resistant tuberculosis itself.

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Where it sits in the disease tree

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↑ Drug-resistant tuberculosis (40)

Including sub-types (11) Tagged with Extensively drug-resistant tuberculosis (5)

Trials to join now! 1 Not yet recruiting 1 Not yet finished but already full! 1 Completed 2

New hope for kids with Drug-Resistant TB: bedaquiline trial launches

Disease control Paused

This study tests a drug called bedaquiline in children and teens (0 months to under 18 years) with multidrug-resistant tuberculosis (MDR-TB), a lung infection that does not respond to standard antibiotics. About 60 participants will receive bedaquiline along with other TB medicat…

Phase 2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control

Last updated Sep 19, 2026 00:00 UTC

Extensively drug-resistant tuberculosis

Where it sits in the disease tree

New hope for kids with Drug-Resistant TB: bedaquiline trial launches