Essential tremor
MONDO:0003233A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10)
Also known as: essential hereditary tremor, tremor, hereditary essential
114 clinical trials for this condition and its sub-types, 102 tagged with Essential tremor itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Essential tremor
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Tremor, hereditary essential, 1 2 trials
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Tremor, hereditary essential, 2 0 trials
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Tremor, hereditary essential, 3 0 trials
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Tremor, hereditary essential, 4 0 trials
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Tremor, hereditary essential, 5 0 trials
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Tremor, hereditary essential, 6 0 trials
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Hair-Thin electrodes tested to Fine-Tune brain stimulation
Symptom relief Not yet recruitingResearchers at Lund University are testing a new way to deliver deep brain stimulation using a cluster of very thin, flexible microelectrodes. The study includes up to 12 adults with Parkinson's disease or essential tremor who are already scheduled for standard deep brain stimula…
Sponsor: Lund University • Aim: Symptom relief
Last updated Sep 17, 2026 00:00 UTC
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Brain zap tweak could quiet shaky hands
Symptom relief Not yet recruitingThis study tests whether using brain images to program deep brain stimulation (DBS) devices works better than the usual method for reducing hand tremors in people with essential tremor. Twenty adults who already have DBS electrodes in their brain will try both programming approac…
Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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New study tests better botox shot for shaky voice
Symptom relief Not yet recruitingThis study compares two ways of giving Botox injections to treat voice tremor, a condition that causes a shaky voice. About 30 adults with essential voice tremor will receive either a standard injection guided by muscle signals or a newer injection into a different part of the vo…
Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Could a gentle brain zap quiet essential tremors?
Symptom relief Not yet recruitingThis small pilot study will test whether a non-invasive electrical stimulation technique called tTIS can reduce tremors in people with essential tremor. Six adults who are already candidates for a standard treatment (focused ultrasound) will receive tTIS to a deep brain area invo…
Sponsor: University Hospital, Geneva • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Sound waves aimed at brain may quiet shaky hands
Symptom relief Not yet recruitingThis study tests whether a precise beam of ultrasound directed at a small part of the brain (the dentate nucleus) can reduce tremor. First, 30 healthy volunteers will have their hand tremor measured during ultrasound to find the best settings. Then, 30 people with essential tremo…
Sponsor: KU Leuven • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Sound waves calm shaky hands in new trial
Symptom relief Not yet recruitingThis study tests if low-intensity focused ultrasound (LIFU) can safely reduce tremors and improve quality of life in people with essential tremor. Twenty adults with hard-to-treat tremors will receive both real LIFU and a fake (sham) treatment in separate sessions to compare effe…
Phase 1/2 • Sponsor: University of Sao Paulo General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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New DBS programming may restore tremor control when standard therapy fails
Symptom relief Not yet recruitingThis study looks at whether new ways of programming deep brain stimulation (DBS) can improve tremor control in adults with essential tremor who stopped responding to standard DBS. Five participants will try six different stimulation settings and use one at home for three months. …
Sponsor: University of British Columbia • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Wearable tech could revolutionize tremor tracking at home
Knowledge-focused Not yet recruitingThis study is testing whether wearable sensors can reliably measure tremor and arm movement in people with Parkinson's disease or Essential Tremor. Participants will wear the sensors during a clinic visit and possibly at home for up to three weeks. The goal is to see if these dev…
Sponsor: Heriot-Watt University • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Brain surgery meets brain science: probing how a memory-related chemical system influences cognition
Knowledge-focused Not yet recruitingThis study investigates how a drug called Cobenfy KarXT, which affects the brain's cholinergic (acetylcholine) system, alters brain activity during memory and thinking tasks. About 30 people with essential tremor or epilepsy who are already scheduled for deep brain stimulation (D…
Early phase 1 • Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC