Eosinophilic fasciitis
MONDO:0009175Eosinophilic fasciitis is a rare connective tissue disease that is characterized by inflammation and thickening of the fascia, usually associated with peripheral eosinophilia. It presents during adulthood with symmetrical and painful swelling of mainly the extremities that progressively become indurated. Fatigue, disabling cutaneous fibrosis, myositis and arthritis may also be observed.
Also known as: Shulman syndrome, diffuse fasciitis with eosinophilia, eosinophilic fasciitis, eosinophilic fasciitis (disease), EF
12 clinical trials for this condition and its sub-types, 1 tagged with Eosinophilic fasciitis itself.
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Immune system overhaul: could CAR T-Cells tame autoimmune disease?
Disease control OngoingThis early-stage trial is testing a new treatment called KYV-101 for people with severe autoimmune diseases like lupus, scleroderma, and vasculitis. The treatment involves taking a patient's own immune cells, modifying them to target and destroy faulty B cells, and giving them ba…
Phase 1 • Sponsor: David Porter • Aim: Disease control
Last updated Sep 21, 2026 13:00 UTC
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New pill could ease rare muscle disease symptoms
Disease control CancelledThis study is testing a drug called deucravacitinib in 10 adults with idiopathic inflammatory myopathies, a group of rare diseases that cause muscle inflammation and weakness. Participants will take one pill daily for 6 months. Researchers will track symptom changes and lab resul…
Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC