Eosinophilic fasciitis
MONDO:0009175Eosinophilic fasciitis is a rare connective tissue disease that is characterized by inflammation and thickening of the fascia, usually associated with peripheral eosinophilia. It presents during adulthood with symmetrical and painful swelling of mainly the extremities that progressively become indurated. Fatigue, disabling cutaneous fibrosis, myositis and arthritis may also be observed.
Also known as: Shulman syndrome, diffuse fasciitis with eosinophilia, eosinophilic fasciitis, eosinophilic fasciitis (disease), EF
12 clinical trials for this condition and its sub-types, 1 tagged with Eosinophilic fasciitis itself.
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Can a new pill ease muscle weakness in myositis?
Disease control Not yet recruitingThis phase III trial tests whether the oral drug nerandomilast can improve symptoms of idiopathic inflammatory myopathies, a group of rare autoimmune diseases that cause muscle weakness and inflammation. Adults with active myositis are randomly assigned to take nerandomilast or a…
Phase 3 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Immune retraining: could CAR-Treg cells tame autoimmune disease?
Disease control Not yet recruitingThis early-phase study tests a new treatment called BEN301, which uses specially engineered immune cells (CAR-Tregs) to calm overactive immune responses in people with autoimmune diseases like scleroderma, rheumatoid arthritis, lupus, and inflammatory muscle disease. The trial wi…
Early phase 1 • Sponsor: Beijing Boren Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC