Endocrine exophthalmos
MONDO:0001509Progressive inflammation and damage to tissues around the eyes, especially extraocular muscle, connective, and fatty tissue occurring in patients with hyperthyroidism or a history of hyperthyroidism due to Graves’ disease.
Also known as: Graves’ eye disease, Graves’ ophthalmopathy, Graves’ orbitopathy, TED, thyroid eye disease, thyroid-associated ophthalmopathy
76 clinical trials for this condition and its sub-types, 76 tagged with Endocrine exophthalmos itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Endocrine exophthalmos
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Exophthalmic ophthalmoplegia 0 trials
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Thyrotoxic exophthalmos 0 trials
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Batoclimab shows promise for thyroid eye disease in extension study
Disease control Stopped earlyThis study is for people who finished earlier trials of batoclimab for thyroid eye disease. It has two parts: one watches how long benefits last without treatment, and the other gives batoclimab to see if it helps more patients. The goal is to see if the drug can control eye bulg…
Phase 3 • Sponsor: Immunovant Sciences GmbH • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Promising drug trial for thyroid eye disease halted early
Disease control Stopped earlyThis study tested a drug called secukinumab in adults with active, moderate to severe thyroid eye disease, a condition that causes bulging eyes and discomfort. The trial aimed to see if the drug could reduce eye bulging and inflammation. However, the study was stopped early and o…
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Experimental K9 pill tested for thyroid eye disease – but study stopped early
Disease control Stopped earlyThis early-phase trial tested an oral drug called K9 (kamuvudine-9) in people with thyroid eye disease, a condition that causes eye bulging and discomfort. The study planned to enroll up to 10 patients but was terminated after only 4 participants. The main goal was to check safet…
Phase 1 • Sponsor: Peter Timoney • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Thyroid eye disease drug trial halted early – no safety concerns
Disease control Stopped earlyThis study tested a drug called efgartigimod for people with active, moderate-to-severe thyroid eye disease, a condition that causes bulging eyes and vision problems. About 102 adults took part, receiving either the drug or a placebo. The trial was stopped early because early res…
Phase 3 • Sponsor: argenx • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Thyroid eye disease drug trial halted after early results disappoint
Disease control Stopped earlyThis study tested a drug called efgartigimod for people with active, moderate-to-severe thyroid eye disease, a condition that causes bulging eyes and vision problems. About 105 adults were randomly assigned to receive either the drug or a placebo as a shot under the skin. The tri…
Phase 3 • Sponsor: argenx • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Brain fatigue after thyroid disease: immune system may be to blame
Knowledge-focused Stopped earlyThis study investigates why some people with Graves' disease continue to feel mentally fatigued even after their thyroid levels return to normal. Researchers will compare blood and spinal fluid from 180 participants—60 with mental fatigue, 60 without, and 60 healthy controls—to f…
Sponsor: Vastra Gotaland Region • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC