Ehlers-Danlos syndrome
MONDO:0020066The Ehlers–Danlos syndromes (EDS) are a clinically and genetically heterogeneous group of heritable connective tissue disorders (HCTDs) characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
Also known as: Danlos Disease, Ehlers, Danlos disease, Disease, Ehlers Danlos, Disease, Ehlers-Danlos, Dystrophia mesodermalis congenita, EDS, Ehler Danlos Syndrome, Ehlers Danlos Disease
46 clinical trials for this condition and its sub-types, 20 tagged with Ehlers-Danlos syndrome itself.
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Sub-types of Ehlers-Danlos syndrome
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Joint laxity, familial 14 trials
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2 sub-types
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Bethlem myopathy 2 0 trials
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1 sub-type
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3 sub-types
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2 sub-types
- Ehlers-Danlos syndrome type 7A 0 trials
- Ehlers-Danlos syndrome, arthrochalasia type, 2 0 trials
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Ehlers-Danlos syndrome, classic type 0 trials
2 sub-types
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2 sub-types
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2 sub-types
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3 sub-types
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2 sub-types
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X-linked Ehlers-Danlos syndrome 0 trials
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Brittle cornea syndrome 0 trials
2 sub-types
- Brittle cornea syndrome 1 0 trials
- Brittle cornea syndrome 2 0 trials
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New pill aims to tame Narcolepsy's sleep attacks and sudden muscle weakness
Disease control Recruiting nowThis study tests whether HBS-301 (pitolisant) can reduce excessive daytime sleepiness and cataplexy (sudden muscle weakness) in adults with narcolepsy. Participants receive either the drug or a placebo for several weeks, followed by an open-label phase where everyone gets the dru…
Phase 3 • Sponsor: Harmony Biosciences Management, Inc. • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Custom stent grafts offer new hope for High-Risk aneurysm patients
Disease control Recruiting nowThis study is testing whether custom-made or physician-modified stent grafts can safely repair complex aortic aneurysms in people who cannot use standard devices or undergo open surgery. The grafts are tailored to each patient's anatomy, with small holes to keep blood flowing to …
Sponsor: Andres Schanzer • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Gentle pilates tested as a pain relief tool for bendy joints
Symptom relief Recruiting nowThis study tests whether Pilates, a gentle mind-body exercise, can help manage pain and other symptoms in people with hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder. One hundred adults with persistent pain will be randomly assigned to either Pilates classes…
Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Aug 21, 2026 00:00 UTC
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Could a laser beam ease the pain of Ehlers-Danlos syndrome?
Symptom relief Recruiting nowThis study tests whether a special laser (MLS class IV) can reduce chronic pain and fatigue in people with hypermobile Ehlers-Danlos syndrome (hEDS), a condition that causes loose joints and widespread pain. Twenty-five adults will receive 10 laser sessions over 5 weeks, with pai…
Sponsor: Centre Medical ISM (Integrative Systemic Medicine) • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New study to reveal if EDS worsens menstrual pain
Knowledge-focused Recruiting nowThis study looks at whether women with Ehlers-Danlos syndrome (EDS) experience more severe period pain than those without the condition. Researchers will compare pain levels and other gynecological issues in 156 women using an online questionnaire. The goal is to better understan…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Battle of the scopes: which endoscopic technique removes rectal tumors best?
Knowledge-focused Recruiting nowThis study looks back at 483 patients who had small rectal neuroendocrine tumors (less than 2 cm) removed using one of two endoscopic techniques: endoscopic submucosal dissection (ESD) or endoscopic partial muscle resection (EPMR). The goal is to compare how often each method lea…
Sponsor: Jilin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Massive study aims to unlock secrets of brain inflammation diseases
Knowledge-focused Recruiting nowThis research study collects health information from 10,000 people with brain inflammation conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to find disease subtypes and…
Sponsor: Brain Inflammation Collaborative • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New EDS registry aims to unlock secrets of rare connective tissue disorder
Knowledge-focused Recruiting nowThis study is building a large registry of up to 3,000 people with Ehlers-Danlos syndrome (EDS) in Italy. Researchers will collect medical history, genetic data, and quality-of-life information to better understand how EDS affects people over time. No new treatments are being tes…
Sponsor: Luca Sangiorgi • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC