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Dysthymic disorder
MONDO:0001442A chronic mood disorder in which the symptoms are similar to, though milder than, those diagnosed in depression.
Also known as: dysthymia
70 clinical trials for this condition and its sub-types, 43 tagged with Dysthymic disorder itself.
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A brain stimulation trial aims to rewire the circuit behind depression
Disease control Not yet recruitingThis trial tests whether transcranial magnetic stimulation (TMS) aimed at a brain circuit linked to the subgenual anterior cingulate cortex can reduce depression symptoms. Adults with major depressive disorder or persistent depressive disorder will receive either active or sham T…
Early phase 1 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Could Pixar's inside out help kids manage anxiety? a new study investigates
Symptom relief Not yet recruitingThis pilot study tests whether MyFILM, a 9-week group program using clips from the movie Inside Out, is feasible and acceptable for children aged 9-12 with mood or anxiety concerns. Participants attend weekly sessions to learn social-emotional skills and coping strategies. The st…
Sponsor: Mark Sinyor • Aim: Symptom relief
Last updated Jul 18, 2026 00:00 UTC
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New therapy aims to lift depression in HIV-Positive teens
Symptom relief Not yet recruitingThis study tests an enhanced version of depression treatment (COMBEX) for youth aged 15-24 with HIV. It combines therapy, medication management, and extra support strategies to improve mood and HIV care. Researchers will compare it to standard combination therapy over 72 weeks in…
Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Quick workout may calm anxiety in mental health patients
Symptom relief Not yet recruitingThis study tests whether a single 'Braining' group exercise session can quickly reduce anxiety in people receiving psychiatric care. Thirty participants will rate their anxiety before and after the session. The goal is to see if exercise can be a fast-acting tool to ease symptoms…
Sponsor: Region Stockholm • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Mental health in the ICU: a 2,000-Patient study aims to uncover hidden risks
Knowledge-focused Not yet recruitingThis study follows 2,000 adults with severe mental illness (such as schizophrenia, bipolar disorder, or severe depression) who are admitted to intensive care units (ICUs) in France. Researchers track their survival and other outcomes for up to 12 months to identify factors that p…
Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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DNA-Guided depression treatment tested in morocco
Knowledge-focused Not yet recruitingThis study tests whether using a person's genetic information can help doctors choose the best antidepressant for major depressive disorder. 570 adults in Morocco will be randomly assigned to either genetic-guided treatment or standard care. Researchers will track depression symp…
Sponsor: Mohammed V University in Rabat • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC