Duodenal ulcer
MONDO:0005412An ulcer in the duodenal wall.
Also known as: duodenal ulcer (disease), stress Ulcer
13 clinical trials for this condition and its sub-types, 7 tagged with Duodenal ulcer itself.
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ICU ulcer prevention drug under scrutiny: does pantoprazole help or harm?
Disease control CompletedThis study tested whether giving pantoprazole (a stomach acid reducer) to critically ill ICU patients prevents stress ulcers and reduces death. Over 3,300 adults at high risk were randomly assigned to receive pantoprazole or a placebo daily while in the ICU. Researchers tracked d…
Phase 4 • Sponsor: Dr. Morten Hylander Møller • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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ICU patients may get fewer unnecessary acid pills thanks to pharmacist checks
Disease control CompletedThis study tested a pharmacist-driven protocol to stop stomach ulcer prevention drugs in ICU patients when they are no longer needed. The goal was to reduce unnecessary medication and side effects without increasing the risk of stomach bleeding. The trial included 120 adult ICU p…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Can a common acid reflux drug keep kids Ulcer-Free?
Disease control CompletedThis completed Phase 3 study tested the drug D961H (esomeprazole) in 50 Japanese children to see if it can prevent reflux esophagitis from coming back and stop stomach or duodenal ulcers from recurring in kids taking NSAIDs or low-dose aspirin. Children took the drug for up to 52…
Phase 3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC