Disease of orbital part of eye adnexa

This study is for people who finished earlier trials of batoclimab for thyroid eye disease. It has two parts: one watches how long benefits last without treatment, and the other gives batoclimab to see if it helps more patients. The goal is to see if the drug can control eye bulg…

This study tested a drug called secukinumab in adults with active, moderate to severe thyroid eye disease, a condition that causes bulging eyes and discomfort. The trial aimed to see if the drug could reduce eye bulging and inflammation. However, the study was stopped early and o…

This early-phase trial tested an oral drug called K9 (kamuvudine-9) in people with thyroid eye disease, a condition that causes eye bulging and discomfort. The study planned to enroll up to 10 patients but was terminated after only 4 participants. The main goal was to check safet…

This study tested a drug called efgartigimod for people with active, moderate-to-severe thyroid eye disease, a condition that causes bulging eyes and vision problems. About 102 adults took part, receiving either the drug or a placebo. The trial was stopped early because early res…

This study tested a drug called efgartigimod for people with active, moderate-to-severe thyroid eye disease, a condition that causes bulging eyes and vision problems. About 105 adults were randomly assigned to receive either the drug or a placebo as a shot under the skin. The tri…

This study investigates why some people with Graves' disease continue to feel mentally fatigued even after their thyroid levels return to normal. Researchers will compare blood and spinal fluid from 180 participants—60 with mental fatigue, 60 without, and 60 healthy controls—to f…