Diabetic ketoacidosis
MONDO:0012819The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.
Also known as: KPD
53 clinical trials for this condition and its sub-types, 22 tagged with Diabetic ketoacidosis itself.
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Could a simple vitamin speed recovery from a dangerous diabetes complication?
Disease control CompletedThis trial tests whether giving intravenous thiamine (vitamin B1) alongside standard treatment helps people with diabetic ketoacidosis recover faster. Diabetic ketoacidosis is a serious condition where the blood becomes too acidic. The study includes adults hospitalized with this…
Phase 2 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New nursing checklist speeds recovery for kids with diabetic crisis
Disease control CompletedThis study tested whether a structured nursing guideline could improve outcomes for children aged 6-16 with diabetic ketoacidosis (DKA), a serious diabetes complication. Sixty children were split into two groups: one received standard care, the other care guided by the new nursin…
Sponsor: Hawler Medical University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Which insulin strategy works best for diabetic ketoacidosis?
Disease control CompletedThis study looked at 100 adults with type 1 diabetes who had diabetic ketoacidosis, a serious complication. Researchers compared three insulin approaches: one without basal insulin, one with basal insulin, and one with both basal and bolus insulin. The goal was to see which metho…
Sponsor: Tanta University • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Diabetes devices put to the test: can home monitors match lab accuracy?
Diagnosis CompletedResearchers are evaluating four blood glucose meters and four HbA1c point-of-care devices to see how accurately they measure blood sugar and long-term glucose control compared with standard lab methods. The study includes people with diabetes, both adults and teenagers, some of w…
Sponsor: Foundation for Innovative New Diagnostics, Switzerland • Aim: Diagnosis
Last updated Sep 19, 2026 00:00 UTC
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Should DKA patients fast or feast? trial tests early eating in the ICU
Symptom relief CompletedDoctors often withhold food from patients being treated for diabetic ketoacidosis in the intensive care unit, but no evidence supports this practice. Researchers are testing whether starting an oral diet early in treatment helps resolve the condition faster and shortens ICU and h…
Sponsor: Texas Tech University Health Sciences Center • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
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Cold spray may take the sting out of insulin shots — a trial puts it to the test
Symptom relief CompletedThis trial tests whether a quick cold spray on the skin before a subcutaneous insulin injection can reduce pain compared to a placebo spray. Adults in the emergency department who need at least two insulin injections receive both sprays in random order, rating their pain after ea…
Sponsor: Abant Izzet Baysal University • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Specially designed insoles could help diabetic patients walk better
Symptom relief CompletedThis study tested custom-made insoles for people with diabetic foot to see if they improve balance and walking. Twenty-five participants aged 40 to 65 with early-stage diabetic foot issues were included. The insoles were designed using pressure measurements to offload high-pressu…
Sponsor: Medipol University • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Family secrets? study maps how relatives talk about genetic health risks
Knowledge-focused CompletedThis study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Can big data map the burden of Diabetes-Related disability?
Knowledge-focused CompletedThis observational study looks at records from Israel's National Insurance Institute to understand how often diabetes is linked to permanent disability. It will compare disability rates and severity across different regions and over time, from 2020 to 2025. No treatments or tests…
Sponsor: Assuta Medical Center • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Talking less meds: training helps doctors cut pills for seniors
Knowledge-focused CompletedThis study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Will tylenol fool your glucose monitor? new study investigates
Knowledge-focused CompletedThis study tested whether taking acetaminophen (like Tylenol) interferes with a new continuous glucose monitor called Biolinq. Thirty-one adults with diabetes wore the Biolinq sensor and a standard CGM for three days. On day three, they took acetaminophen and researchers compared…
Sponsor: Biolinq Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Gene hunt aims to predict deadly diabetes drug complication
Knowledge-focused CompletedThis study looked at whether a person's genes can help predict their risk of diabetic ketoacidosis (DKA) when taking SGLT2 inhibitors, a common class of diabetes drugs. Researchers collected DNA from 63 adults with type 2 diabetes who were either hospitalized with DKA while on th…
Sponsor: Mount Sinai Hospital, Canada • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Scientists map how lifestyle changes tweak your Body's sugar control
Knowledge-focused CompletedThis completed study looked at how diet and exercise change blood sugar levels in 61 adults with diabetes. Researchers used advanced tests (genomics, proteomics, etc.) to understand the body's complex response. The goal is to build a tool that helps doctors personalize diabetes c…
Sponsor: Shanghai 6th People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC