Diabetic ketoacidosis
MONDO:0012819The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.
Also known as: KPD
53 clinical trials for this condition and its sub-types, 22 tagged with Diabetic ketoacidosis itself.
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Could a simple vitamin speed recovery from a dangerous diabetes complication?
Disease control CompletedThis trial tests whether giving intravenous thiamine (vitamin B1) alongside standard treatment helps people with diabetic ketoacidosis recover faster. Diabetic ketoacidosis is a serious condition where the blood becomes too acidic. The study includes adults hospitalized with this…
Phase 2 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New nursing checklist speeds recovery for kids with diabetic crisis
Disease control CompletedThis study tested whether a structured nursing guideline could improve outcomes for children aged 6-16 with diabetic ketoacidosis (DKA), a serious diabetes complication. Sixty children were split into two groups: one received standard care, the other care guided by the new nursin…
Sponsor: Hawler Medical University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Which insulin strategy works best for diabetic ketoacidosis?
Disease control CompletedThis study looked at 100 adults with type 1 diabetes who had diabetic ketoacidosis, a serious complication. Researchers compared three insulin approaches: one without basal insulin, one with basal insulin, and one with both basal and bolus insulin. The goal was to see which metho…
Sponsor: Tanta University • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Should DKA patients fast or feast? trial tests early eating in the ICU
Symptom relief CompletedDoctors often withhold food from patients being treated for diabetic ketoacidosis in the intensive care unit, but no evidence supports this practice. Researchers are testing whether starting an oral diet early in treatment helps resolve the condition faster and shortens ICU and h…
Sponsor: Texas Tech University Health Sciences Center • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
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Gene hunt aims to predict deadly diabetes drug complication
Knowledge-focused CompletedThis study looked at whether a person's genes can help predict their risk of diabetic ketoacidosis (DKA) when taking SGLT2 inhibitors, a common class of diabetes drugs. Researchers collected DNA from 63 adults with type 2 diabetes who were either hospitalized with DKA while on th…
Sponsor: Mount Sinai Hospital, Canada • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC