Desmoplastic small round cell tumor
MONDO:0019373Desmoplastic small round cell tumor (DSRCT) is an aggressive soft tissue cancer that typically arises in serous lined surfaces of the abdominal or pelvic peritoneum, and spreads to the omentum, lymph nodes and hematogenously disseminates especially to the liver. Extraserous primary location has been reported in exceptional cases.
Also known as: DSRCT, Desmoplas. small round cell tumor, Desmoplas. small round cell tumour, Desmoplastic small round cell tumor, Desmoplastic small round cell tumour, Desmoplastic small round-cell neoplasm, Desmoplastic small round-cell tumor, Desmoplastic small round-cell tumour
2846 clinical trials for this condition and its sub-types, 26 tagged with Desmoplastic small round cell tumor itself.
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New hope for tough childhood cancers: targeted drug combo under study
Disease control CompletedThis study tests a new combination of drugs (temsirolimus, temozolomide, and irinotecan) for children and young adults with high-risk Ewing sarcoma or desmoplastic small round cell tumors. Participants are split into standard-risk and high-risk groups, with high-risk patients rec…
Phase 2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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New hope for kids with rare abdominal cancer: drug combo tested
Disease control CompletedThis study tested a drug called ramucirumab, given with standard chemotherapy, for children and young adults with a rare cancer called desmoplastic small round cell tumor (DSRCT) that had come back or not responded to treatment. The goal was to see if the combination could slow t…
Phase 1/2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Can a simple test predict who will respond to this sarcoma drug?
Knowledge-focused CompletedThis study aims to find biological markers that can predict whether the drug trabectedin will work in patients with certain types of soft-tissue sarcoma. Researchers will collect tumor biopsies and blood samples from 29 participants before and during treatment. The goal is to use…
Sponsor: Institut Bergonié • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC