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Can a simple test predict who will respond to this sarcoma drug?

NCT ID NCT04008238

First seen Nov 01, 2025

Summary

This study aims to find biological markers that can predict whether the drug trabectedin will work in patients with certain types of soft-tissue sarcoma. Researchers will collect tumor biopsies and blood samples from 29 participants before and during treatment. The goal is to use advanced testing to identify which patients are most likely to benefit, potentially leading to more personalized treatment decisions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Institut Bergonie

    Bordeaux, 33076, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

trabectedin

What this could lead to

If successful, this could help doctors identify which sarcoma patients are most likely to benefit from trabectedin, making treatment more personalized.

What could go wrong

This is a small, early-stage study focused on finding biomarkers, not on proving treatment effectiveness. The results may not apply to all sarcoma types or lead to immediate changes in care.

Conditions

The condition(s) this trial relates to.

desmoplastic small round cell tumor epithelioid sarcoma hemangioendothelioma sarcoma soft tissue sarcoma solitary fibrous tumor synovial sarcoma undifferentiated pleomorphic sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.