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Degenerative myopia
MONDO:0001383Excessive axial myopia associated with complications (especially posterior staphyloma and choroidal neovascularization) that can lead to blindness.
Also known as: progressive high (degenerative) myopia
48 clinical trials for this condition and its sub-types, 38 tagged with Degenerative myopia itself.
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New drug faricimab takes on leading cause of blindness in nearsighted people
Disease control CompletedThis study tested a drug called faricimab (VABYSMO®) against an existing treatment (ranibizumab) for people with vision loss caused by abnormal blood vessels growing in the back of the eye due to severe nearsightedness. The trial involved 280 participants who received either fari…
Phase 3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Eye drops could keep Kids' vision from getting worse
Disease control CompletedThis study tested three low doses of atropine eye drops (0.01%, 0.03%, and 0.05%) in 95 children aged 6–18 with nearsightedness. The goal was to see which dose best slowed the worsening of myopia with the fewest side effects. Over 18 months, the 0.05% dose worked best at controll…
Phase 3 • Sponsor: Khyber Medical College, Peshawar • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Can bifocals plus eye drops beat drops alone for Kids' nearsightedness?
Disease control CompletedThis study looked at whether adding bifocal glasses to daily atropine eye drops works better than atropine alone to slow down nearsightedness (myopia) in children. 210 kids aged 4-16 with worsening myopia took part. The main goal was to measure changes in their vision prescriptio…
Sponsor: University of Faisalabad • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Can a nightly eye drop tame severe nearsightedness in kids?
Disease control CompletedThis study tested three strengths of atropine eye drops (0.01%, 0.04%, and 0.1%) in 219 children with high myopia (severe nearsightedness). The goal was to see which dose best slows the worsening of vision and eye growth over two years. Children received one drop in each eye ever…
Sponsor: Shanghai Eye Disease Prevention and Treatment Center • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New combo therapy may slow severe nearsightedness in kids
Disease control CompletedThis study tested whether combining low-dose atropine eye drops with special soft contact lenses can slow the progression of high myopia (severe nearsightedness) in children aged 6-12. 120 children were split into three groups: one got the combo therapy, one got atropine alone wi…
Phase 4 • Sponsor: Beijing Tongren Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Can 3D screens sharpen cataract surgery for very nearsighted eyes?
Knowledge-focused CompletedThis trial asks whether using a 3D visualization system during cataract surgery helps surgeons operate more smoothly in people with high myopia (very nearsighted eyes). It compares the 3D system to a traditional optical microscope, measuring how often the surgeon needs to adjust …
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Could eye pigment levels predict vision damage in severe nearsightedness?
Knowledge-focused CompletedThis study examined 39 people with severe nearsightedness to see if lower levels of a natural eye pigment (macular pigment) are linked to tiny cracks in the back of the eye called lacquer cracks. These cracks can lead to vision loss. The researchers measured the pigment's optical…
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC