Cutaneous lupus erythematosus

This study tested an extra dose of the HIPRA COVID-19 vaccine in 241 adults with conditions like HIV, kidney disease, or autoimmune disorders that weaken the immune system. The goal was to see if the booster raises antibody levels against virus variants and remains safe. Research…

This early-stage trial tests the safety and tolerability of SOF-SKN, a cream applied to the skin, in healthy volunteers aged 18 to 64. The study has two parts: one applies a single dose, and the other applies daily doses for two weeks, with escalating strengths. Researchers monit…

This early-phase study tested a new drug called BMS-986326 in 45 adults with different forms of lupus, including skin and systemic lupus. The main goal was to check safety and how the body processes the drug, not yet to see if it works. Participants received either the drug or a …

This early-phase trial tested a new drug called VIS171 in 61 people: first in healthy volunteers, then in patients with autoimmune diseases. The main goal was to check safety and how the body processes the drug. No results on whether it actually helps the disease are available ye…

This study tested the drug tofacitinib in 13 young adults aged 18 to 45 with moderate to severe lupus skin disease. The goal was to see if the drug is safe and can reduce skin symptoms. Participants took the drug for up to 76 weeks, and doctors measured how well it worked using a…

This study tested an experimental drug called enpatoran in 456 people with lupus, a chronic autoimmune disease. Participants took either a low, medium, or high dose of enpatoran or a placebo for 24 weeks. The goal was to see if the drug safely reduces skin and overall disease act…

This study looked at a device called GLOBAFFIN that filters antibodies from the blood to help people with autoimmune diseases. It involved 34 adults and measured how much harmful antibodies were removed and if patients felt better. The goal was to see if the device is safe and wo…

This study looked at whether a diet low in salt and sugar can reduce common side effects of corticosteroid treatment, such as weight gain, high blood pressure, and diabetes. Fifty adults with autoimmune diseases or asthma who were starting high-dose corticosteroids were randomly …

This study looked at 719 people, including patients with autoimmune connective tissue diseases like myositis, their blood relatives, and healthy volunteers. Researchers collected blood samples and medical histories to find genetic and environmental factors that may trigger these …

This study looked at over 13,000 people with chronic inflammatory rheumatism or autoimmune diseases who had or were suspected to have COVID-19. Researchers tracked how many developed severe COVID-19 requiring intensive care or leading to death. They also examined risk factors lik…

This study looked at 202 adults with cutaneous lupus to see how well they follow their treatment plans and how satisfied they are with their care. Researchers used questionnaires to measure adherence, beliefs about medicine, anxiety, depression, and quality of life. The goal is t…

This completed study followed 73 people with autoimmune diseases like rheumatoid arthritis or multiple sclerosis who were starting treatment with rituximab. The goal was to track how many developed serious infections and to understand what factors increase that risk. Researchers …

This early-phase study tested the safety and tolerability of a new drug called LAD191 in 69 healthy adults and people with an autoimmune disease. Researchers gave single or multiple doses to see how the body processes the drug and if it causes side effects. The goal was to gather…