Corticobasal degeneration disorder

MONDO:0022308

A progressive neurodegenerative condition affecting the cerebral cortex and basal ganglia. The disorder is characterized by varying degrees of cognitive and motor impairment.

Also known as: cortical basal ganglionic degeneration, corticobasal degeneration, CBGD, cortical-basal ganglionic degeneration, cortico-basal ganglionic Degeneration (CBGD), corticobasal syndrome, corticodentatonigral degeneration with neuronal achromasia

28 clinical trials for this condition and its sub-types, 28 tagged with Corticobasal degeneration disorder itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Syndromic disease (7133) ↑ Cerebral degeneration (61)

Including sub-types (28) Tagged with Corticobasal degeneration disorder (28)

Trials to join now! 14 Not yet recruiting 4 Not yet finished but already full! 7 Completed 2 Terminated 1

Experimental drug aims to curb disinhibition in dementia patients

Symptom relief Stopped early

This study tested a drug called AVP-786 to see if it could safely reduce disinhibition—impulsive or inappropriate behavior—in people with neurodegenerative disorders like Alzheimer's or frontotemporal dementia. The trial planned to include many participants but was terminated ear…

Phase 2 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Symptom relief

Last updated Jun 27, 2026 12:32 UTC

Corticobasal degeneration disorder

Where it sits in the disease tree

Experimental drug aims to curb disinhibition in dementia patients