Corneal ulcer
MONDO:0004577Area of epithelial tissue loss from corneal surface; associated with inflammatory cells in the cornea and anterior chamber.
Also known as: Ulcer, corneal, cornea ulcer disease, ulcer disease of cornea
25 clinical trials for this condition and its sub-types, 16 tagged with Corneal ulcer itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Corneal ulcer
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Mooren ulcer 1 trial
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Marginal corneal ulcer 1 trial
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Central corneal ulcer 0 trials
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Mycotic corneal ulcer 0 trials
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Perforated corneal ulcer 0 trials
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Ring corneal ulcer 0 trials
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Green light and pink dye take on tough eye infections
Disease control CompletedThis study tested whether adding a light-activated dye (rose bengal) to standard antibiotic or antifungal eye drops could improve vision in people with severe corneal infections. About 330 adults in India and Brazil with fungal or amoeba infections received either standard drops …
Phase 3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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New membrane could speed healing of eye infections
Disease control CompletedThis study tested whether adding a special amniotic membrane containing riboflavin and moxifloxacin to standard PACK-CXL therapy helps heal infected corneal ulcers faster. 32 adults with moderate-to-severe ulcers took part. The goal was to see if the membrane improves corneal hea…
Phase 2 • Sponsor: Gadjah Mada University • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Eye injection shows promise against fungal ulcers
Disease control CompletedThis study tested whether adding an injection of the antifungal drug voriconazole into the eye could improve treatment for fungal corneal ulcers. 70 people with moderate to severe infections received either standard antifungal drops alone or drops plus three injections over 10 da…
Phase 3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Can village volunteers stop eye ulcers before they start?
Prevention CompletedThis trial tests whether training female community health volunteers to diagnose and treat corneal abrasions can prevent corneal ulcers across many villages. Volunteers treat eye scratches with antifungal and antibiotic ointments three times a day for three days. Researchers comp…
Sponsor: University of California, San Francisco • Aim: Prevention
Last updated Sep 16, 2026 00:00 UTC
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New eye insert may ease pain after cataract surgery
Symptom relief CompletedThis study tested whether a tiny eye insert called DEXTENZA, placed after cataract surgery, works better than standard eye drops alone for reducing pain and swelling. Fifty adults having cataract surgery took part. The insert slowly releases medicine over time, aiming to improve …
Phase 4 • Sponsor: Nicole Fram M.D. • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Stem cell eye drops show promise for Hard-to-Treat corneal damage
Symptom relief CompletedThis early-stage study tested the safety of eye drops made from stem cell secretions in 9 adults with chronic corneal surface disease that did not improve with standard treatments. The drops were given in increasing doses to find the safest amount. Researchers checked for side ef…
Early phase 1 • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC