Corneal ulcer
MONDO:0004577Area of epithelial tissue loss from corneal surface; associated with inflammatory cells in the cornea and anterior chamber.
Also known as: Ulcer, corneal, cornea ulcer disease, ulcer disease of cornea
25 clinical trials for this condition and its sub-types, 16 tagged with Corneal ulcer itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Corneal ulcer
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Mooren ulcer 1 trial
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Marginal corneal ulcer 1 trial
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Central corneal ulcer 0 trials
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Mycotic corneal ulcer 0 trials
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Perforated corneal ulcer 0 trials
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Ring corneal ulcer 0 trials
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New injection could beat tough eye infections that drops Can't handle
Disease control Recruiting nowThis study tests whether injecting the antibiotic moxifloxacin directly into the cornea can help treat bacterial eye infections that don't improve with standard antibiotic drops. About 60 adults with stubborn corneal infections will receive either the injection plus drops or drop…
Sponsor: Minia University • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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New eye drop combo could save sight from fungal infections
Disease control Recruiting nowThis study tests whether adding cyclosporine A eye drops to standard natamycin treatment helps people with fungal keratitis (a serious eye infection). About 150 adults with confirmed fungal infection will receive either a low or high dose of cyclosporine A or a placebo for 4 week…
Phase 3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Could steroids save sight in parasitic eye disease?
Disease control Recruiting nowThis Phase 3 trial tests whether adding steroid eye drops to standard anti-parasitic treatment improves vision in people with acanthamoeba keratitis, a rare but serious eye infection. About 232 participants who still have eye inflammation after one month of standard care will rec…
Phase 3 • Sponsor: Jeremy Keenan, MD, MPH • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Stem cells offer new hope for stubborn eye ulcers
Disease control Recruiting nowThis study tests whether injecting stem cells into the eye can help heal corneal ulcers that haven't improved with standard treatments. The stem cells are donated from healthy volunteers and processed in a lab. About 38 adults with persistent eye surface damage will receive the i…
Phase 2 • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Texting patients to save sight: SMS reminders tested for corneal ulcer care
Knowledge-focused Recruiting nowThis study looks at whether sending SMS reminders can improve how often patients with corneal ulcers come back for follow-up visits at an eye hospital in Nepal. About 310 adults aged 18 to 70 who own a mobile phone will take part. The goal is to see if a simple text message can h…
Sponsor: Seva Canada Society • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC