Please sign in to follow a disease.
Congenital isolated hyperinsulinism
MONDO:0019010Congenital isolated hyperinsulinism (CHI), a rare endocrine disease is the most frequent cause of severe and persistent hypoglycemia in the neonatal period and early infancy and is characterized by an excessive or uncontrolled insulin secretion (inappropriate for the level of glycemia) and recurrent episodes of profound hypoglycemia requiring rapid and intensive treatment to prevent neurological sequelae. CHI comprises 2 different forms: diazoxide-sensitive diffuse hyperinsulinism and diazoxide-resistant hyperinsulinism.
Also known as: Congenital Hyperinsulinism, PHHI, chi, persistent hyperinsulinemic hypoglycemia of infancy, congenital hyperinsulinism, hyperinsulinemic hypoglycemia familial, hyperinsulinism congenital, hyperinsulinism familial with pancreatic nesidioblastosis
2 clinical trials for this condition and its sub-types, 0 tagged with Congenital isolated hyperinsulinism itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Congenital isolated hyperinsulinism
-
Diazoxide-sensitive diffuse hyperinsulinism 0 trials · 2 incl. sub-types
8 sub-types
- Exercise-induced hyperinsulinism 1 trial
- Hyperinsulinism-hyperammonemia syndrome 1 trial
- Autosomal dominant hyperinsulinism due to Kir6.2 deficiency 0 trials
- Autosomal dominant hyperinsulinism due to SUR1 deficiency 0 trials
- Hyperinsulinemic hypoglycemia, familial, 4 0 trials
- Hyperinsulinism due to HNF1A deficiency 0 trials
- Hyperinsulinism due to HNF4A deficiency 0 trials
- Hyperinsulinism due to UCP2 deficiency 0 trials
-
Diazoxide-resistant hyperinsulinism 0 trials
2 sub-types