Congenital glaucoma
MONDO:0020366A developmental glaucoma that results from the abnormal development of the aqueous drainage structure, characterized by an elevated intra-ocular pressure, enlargement of globe (buphthalmos), corneal edema and optic nerve cupping, and presenting clinically with the characteristic triad of epiphora, photophobia and blepharospasm.
Also known as: Buphthalmus, buphthalmia, buphthalmos, hydrophthalmos, primary congenital glaucoma
16 clinical trials for this condition and its sub-types, 7 tagged with Congenital glaucoma itself.
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Sub-types of Congenital glaucoma
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Primary congenital glaucoma 3 trials · 5 incl. sub-types
3 sub-types
- CYP1B1-related glaucoma with or without anterior segment dysgenesis 0 trials · 2 incl. sub-types Sub-types →
- Glaucoma 3, primary congenital, C 0 trials
- Glaucoma 3, primary congenital, D 0 trials
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Glaucoma 3, primary congenital, E 0 trials
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Glaucoma 3, primary infantile, B 0 trials
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Glaucoma type 1C 0 trials
Most studied deeper sub-types
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Can a simple office procedure ease glaucoma pressure?
Disease control Not yet recruitingThis study tests whether removing the ripcord from a glaucoma drainage device more than 3 months after placement lowers eye pressure. Adults with glaucoma who have had the ripcord in place for over 3 months will have it removed during a routine clinic visit. Researchers will meas…
Sponsor: Duke University • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Which eye implant best tames glaucoma? a head-to-head trial aims to find out.
Disease control Not yet recruitingThis trial compares two surgical implants—the Baerveldt Glaucoma Implant and the Paul Glaucoma Implant—in people with glaucoma that is not well controlled by eye drops. Both devices are tiny tubes placed in the eye to drain fluid and lower pressure. The study will track which imp…
Phase 4 • Sponsor: University of Sydney • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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How much eye surgery is best for babies with glaucoma?
Disease control Not yet recruitingThis study looks at children with a rare, severe eye disease called primary congenital glaucoma. It compares three different amounts of a surgery called goniotomy (120°, 240°, or 360°) to see which works best and is safest. The goal is to lower eye pressure and protect vision, bu…
Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New study tests best breathing tube for Kids' eye surgery
Knowledge-focused Not yet recruitingThis study looks at how different ways of managing a child's airway during anesthesia affect eye pressure and heart rate in children having surgery for congenital glaucoma. 75 children will be split into three groups, each receiving a different airway device. The goal is to find …
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC