Complex regional pain syndrome

This trial tests whether transcranial electrical stimulation (tES) — a safe, non-invasive technique that sends a mild electrical current through the scalp — can reduce pain and improve quality of life in children and adolescents aged 10 to 21 with juvenile fibromyalgia or other n…

This study tests whether combining virtual reality games with physical therapy can reduce chronic pain in children aged 7 to 21. Twenty participants with pain in the head, neck, or upper limbs will attend six weekly sessions. They will play VR games designed to encourage movement…

This phase 2 trial will test whether extended-release ketamine tablets can reduce pain in 65 adults with complex regional pain syndrome (CRPS), a chronic condition causing severe, often burning pain. Participants will take either 80 mg or 160 mg of ketamine daily for several week…

This study tests whether a very low dose of naltrexone, a drug usually used for addiction, can reduce pain and other symptoms in people with Complex Regional Pain Syndrome (CRPS). Forty adults with CRPS will receive either the drug or a placebo for six months. The main goal is to…

This study tests whether repeated magnetic pulses (rTMS) aimed at the brain's motor area can safely reduce chronic nerve pain that hasn't responded to other treatments. About 32 adults with conditions like post-stroke pain, trigeminal neuralgia, or spinal cord injury will receive…

This study looks at adults with chronic pain who receive ketamine infusions at Stanford's Pain Management Center. Researchers want to understand which patients improve and what factors predict a good response. The goal is to better tailor this treatment to individuals.

This study looks back at medical records of 200 adults with Complex Regional Pain Syndrome (CRPS) to see which pain treatments doctors actually use first and how well they work. Researchers want to find patterns that could help choose the best treatment for each person. No new tr…

This study planned to use Apple Watches to track physical activity, diet, and environment in children with complex regional pain syndrome (CRPS) to identify what triggers sudden severe pain. However, the study was withdrawn before enrolling any participants, so no data was collec…

This study is enrolling 120 adults with Complex Regional Pain Syndrome (CRPS) to see if certain blood clotting factors are linked to how well they respond to neridronic acid treatment. Researchers will measure pain levels before and after treatment. The goal is to find markers th…

This study follows 100 people with combat-related limb injuries to see if the mechanics of the injury—like force and direction—can predict who will develop chronic pain. Researchers will track pain levels at 3 and 6 months. The goal is to find early warning signs so doctors can s…

This study aims to validate a self-report questionnaire that people with Complex Regional Pain Syndrome (CRPS) can fill out at home. Researchers will compare the self-report results with in-person clinical exams to see if the questionnaire accurately measures symptom severity and…

This study reviews the medical records of 20 adults who had a limb amputated to relieve severe, long-lasting pain from complex regional pain syndrome (CRPS). Researchers want to measure how many days pass between the amputation and when patients first use a functional prosthetic …