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Amputation for pain: how long until patients walk again?

NCT ID NCT07364266

Knowledge-focused Sponsor: University Hospital, Brest Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study reviews the medical records of 20 adults who had a limb amputated to relieve severe, long-lasting pain from complex regional pain syndrome (CRPS). Researchers want to measure how many days pass between the amputation and when patients first use a functional prosthetic limb. They also track when patients return to physical or leisure activities. The goal is to improve knowledge and care for others facing this difficult choice.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict recovery timelines and improve care for patients who need amputation for severe, untreatable pain.
What could go wrong
This is a very small, observational review of only 20 patients, so results may not apply to everyone. It does not test a new treatment or compare options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

20 people

The number who actually took part.

Started

Sep 2025

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study concerns a population of patients who underwent lower- or upper-limb amputation for post-traumatic algodystrophy, managed at CHRU de Brest between 2010 and 2025. This rare and specific indication relies on a multidisciplinary medical decision after a prolonged pathway in a pain center, justifying rigorous and homogeneous population selection.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients at the time of amputation; Post-traumatic algodystrophy diagnosed clinically and confirmed by imaging if necessary, according to the Budapest criteria; Amputation performed for analgesic purposes, after failure of conventional medical and rehabilitation treatments; Postoperative follow-up carried out at CHRU de Brest, with available data on prosthetic fitting and postoperative activities; Complete medical record accessible via the hospital electronic medical record. Exclusion Criteria: * Patients amputated for another cause (vascular, tumor, infectious, etc.); Patients not followed after amputation or immediately lost to follow-up after surgery; Incomplete medical records regarding the main variables of interest (dates of amputation, prosthetic fitting, functional follow-up).

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Conditions

The condition(s) this trial relates to.

complex regional pain syndrome complex regional pain syndrome type 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Algoneurodystrophy Amputation

Contacts and locations

Locations

  • CHU de Brest

    Brest, France

  • Chu Brest

    Brest, 29200, France

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