Colonic disorder
MONDO:0003409Pathological processes in the colon region of the large intestine (intestine, large).
Also known as: colon disease, colon disease or disorder, disease of colon, disease or disorder of colon, disorder of colon
1471 clinical trials for this condition and its sub-types, 18 tagged with Colonic disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Colonic disorder
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Colitis 41 trials · 679 incl. sub-types
9 sub-types
- Ulcerative colitis 581 trials Sub-types →
- Infectious colitis 0 trials · 69 incl. sub-types Sub-types →
- Indeterminate colitis 26 trials
- Proctocolitis 2 trials · 7 incl. sub-types Sub-types →
- Ileocolitis 5 trials
- Microscopic colitis 3 trials · 5 incl. sub-types Sub-types →
- Chemical colitis 3 trials
- Diversion colitis 2 trials
- Ischemic colitis 0 trials
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Colonic neoplasm 461 trials · 635 incl. sub-types
8 sub-types
- Malignant colon neoplasm 62 trials · 439 incl. sub-types Sub-types →
- Epithelial tumor of colon 0 trials · 409 incl. sub-types Sub-types →
- Cecal neoplasm 0 trials · 59 incl. sub-types Sub-types →
- Sigmoid neoplasm 7 trials · 17 incl. sub-types Sub-types →
- Colon neuroendocrine neoplasm 0 trials · 5 incl. sub-types Sub-types →
- Benign colon neoplasm 2 trials Sub-types →
- Colon inflammatory polyp 0 trials
- Colon juvenile polyp 0 trials
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Cecal disorder 0 trials · 135 incl. sub-types
2 sub-types
- Appendicitis 76 trials
- Cecal neoplasm 0 trials · 59 incl. sub-types Sub-types →
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Polyp of colon 55 trials · 73 incl. sub-types
5 sub-types
- Adenomatous colon polyp 12 trials
- Colon sessile serrated adenoma/polyp 11 trials
- Colon serrated polyposis 1 trial
- Colon inflammatory polyp 0 trials
- Colon juvenile polyp 0 trials
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Diverticulitis of colon 19 trials
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Functional colonic disease 13 trials
1 sub-type
- Colonic pseudo-obstruction 0 trials
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Colon dysplasia 4 trials
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Functional diarrhea 4 trials
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Megacolon 2 trials
1 sub-type
- Toxic megacolon 0 trials
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Sigmoid disease 2 trials
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Chilaiditi syndrome 0 trials
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Colonic duplication 0 trials
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Neuronal intestinal dysplasia 0 trials
2 sub-types
Most studied deeper sub-types
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New stapler aims to reduce leaks after colon surgery
Disease control Recruiting nowThis study is testing a new surgical stapler, called the Signia circular stapler, in people having left-sided colon, sigmoid, or rectal surgery. The goal is to see if it lowers the chance of a leak where the colon is reconnected. About 137 adults will take part, and the main focu…
Sponsor: Medtronic - MITG • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Real-world study tracks guselkumab's impact on IBD patients
Disease control Recruiting nowThis study will follow 500 people with Crohn's disease or ulcerative colitis who are starting guselkumab, a biologic drug. Researchers will measure how many achieve remission and how the treatment affects daily life, including fatigue and work productivity. The goal is to underst…
Sponsor: Janssen-Cilag G.m.b.H • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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New hope for liver cancer patients who have no other options
Disease control Recruiting nowThis study is testing a treatment called BSJ019T in Japanese patients with liver cancer that cannot be removed by surgery and has not responded to standard treatments. The goal is to see if the treatment can control the cancer's growth and how safe it is. About 51 participants wi…
Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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New hope for colorectal cancer: experimental drug faces off against avastin
Disease control Recruiting nowThis Phase 3 trial is testing whether a new medicine called PF-08634404, combined with standard chemotherapy, works better than the current treatment Avastin plus chemo for people whose colorectal cancer has spread. About 800 participants who have not had prior treatment for meta…
Phase 3 • Sponsor: Pfizer • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New drug combo aims to tame ulcerative colitis
Disease control Recruiting nowThis study tests two drugs, eltrekibart and mirikizumab, alone or together, in 140 adults with moderate-to-severe ulcerative colitis. The goal is to see if they can safely reduce inflammation and help patients achieve remission. Participants must have tried other treatments witho…
Phase 2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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New targeted drug shows promise for Hard-to-Treat cancers
Disease control Recruiting nowThis study tests a new drug called repotrectinib in people with advanced solid tumors that have certain gene changes (ALK, ROS1, or NTRK). The trial has two parts: first, finding a safe dose, and second, seeing how well the drug shrinks tumors. About 500 adults with advanced canc…
Phase 1/2 • Sponsor: Turning Point Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Blood test could spot colon cancer before it spreads
Diagnosis Recruiting nowThis study is testing a blood test (called a liquid biopsy) to see if it can find colorectal cancer, pre-cancerous growths (adenomas), and cancers linked to Lynch syndrome at an early stage. Researchers will enroll 1,200 people who have already had a colonoscopy. The goal is to s…
Sponsor: San Raffaele University • Aim: Diagnosis
Last updated Jun 27, 2026 09:11 UTC
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Can we predict and treat cancer wasting better? a new study investigates
Knowledge-focused Recruiting nowThis study is looking at why some people with advanced cancer lose weight and muscle, a condition called cachexia. Researchers will follow 800 patients with advanced lung, pancreatic, or colorectal cancer to see if there are distinct subtypes of cachexia based on symptoms, biomar…
Sponsor: Kaiser Permanente • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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Can a Low-Cysteine diet lower colon cancer risk? new study investigates
Knowledge-focused Recruiting nowThis study looks at how eating different amounts of cysteine—a protein building block—affects gut bacteria and inflammation in people at higher risk for colon cancer. Researchers will compare Black and White adults aged 45-75 who have had colon polyps. Participants will follow bo…
Sponsor: Purdue University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC