CNS demyelinating autoimmune disease
MONDO:0006704Conditions characterized by loss or dysfunction of myelin (see myelin sheath) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or oligodendroglia associated autoantigens.
888 clinical trials for this condition and its sub-types, 5 tagged with CNS demyelinating autoimmune disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of CNS demyelinating autoimmune disease
-
Multiple sclerosis 765 trials · 852 incl. sub-types
4 sub-types
- Relapsing-remitting multiple sclerosis 262 trials
- Chronic progressive multiple sclerosis 81 trials · 113 incl. sub-types Sub-types →
- Pediatric multiple sclerosis 5 trials
- Marburg acute multiple sclerosis 0 trials
Most studied deeper sub-types
-
Strumming for the brain: could ukulele lessons sharpen minds in MS?
Symptom relief Recruiting nowThis study tests whether a 12-week online ukulele learning program, called Music-4-MS, can improve cognitive function in people with multiple sclerosis (MS). Half the participants will learn to play the ukulele, while the other half will simply listen to music they enjoy. The goa…
Sponsor: University of Texas at Austin • Aim: Symptom relief
Last updated Aug 19, 2026 00:00 UTC
-
Scientists track brain lesions over years to unlock MS mysteries
Knowledge-focused Recruiting nowThis observational study follows 170 people with multiple sclerosis, neuromyelitis optica, and similar conditions, plus healthy volunteers, for up to 6 years. Researchers use MRI scans, blood tests, and spinal fluid analysis to monitor brain lesions and understand how the disease…
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC