Circadian rhythm sleep disorder, shift work type

This European trial tests a 24-week lifestyle program for 400 night-shift workers. The program, delivered via a mobile app and workshops, focuses on sleep, stress, diet, and exercise. The goal is to see if it helps workers sleep longer and improve their health.

This study looks at whether time-restricted eating (eating only during certain hours) can improve blood pressure and insulin sensitivity in people who work night shifts. Night shift workers are at higher risk for heart disease and type 2 diabetes. Researchers will compare 4 weeks…

This study looks at whether adjusting meal timing can reduce health risks for night-shift nurses and nursing assistants who are overweight. Participants will either just track their diet, follow a 10-hour daytime eating window, or add a low-sugar snack during night shifts. The go…

This Phase 3 trial tests whether the drug solriamfetol can reduce excessive sleepiness in people with shift work disorder. About 520 adults who work night shifts will take either solriamfetol or a placebo daily for 12 weeks. The study measures how well they stay awake and their o…

This study tests a mobile app called SHIFT that uses data from an Apple Watch to give personalized light exposure advice, helping night shift workers sleep better. Researchers will enroll 300 night shift workers who have poor sleep. The goal is to see if the app improves sleep, h…

This study looks at how losing sleep and having a disrupted body clock (like shift workers) can make the body less responsive to insulin, a key step toward obesity and type 2 diabetes. Researchers will test 48 healthy adults aged 18-45 to see how the timing of the stress hormone …

This study aims to understand how working night shifts impacts blood sugar, fat levels, and heart health in hospital staff. Researchers will compare workers who do night shifts with those who don't, using continuous glucose monitors and other measurements. The goal is to gather k…

This study looks at how working rotating or night shifts in heavy industry affects workers' body clocks, sleep, muscle pain, and overall quality of life. Researchers will ask participants to fill out questionnaires about their sleep habits, pain, and well-being. The goal is to be…

This study looks at whether taking a nap during a night shift can improve blood pressure and alertness in healthcare and public safety workers. Researchers will compare naps lasting 0, 15, 30, 45, or 60 minutes taken at 2:00 AM. The goal is to find the nap length that best balanc…

This study aims to improve how sleep is measured for nightshift workers, whose inverted schedules make standard sleep trackers inaccurate. Researchers will use an Apple Watch along with machine learning to better detect daytime sleep. About 100 nightshift workers will participate…

This study looks at whether working unusual hours or having idle time at work makes people more likely to gamble in risky ways. Researchers will interview 25 adults who currently have or have had gambling problems and who have worked in the past year. The goal is to understand ho…

This study looks at whether providing meals to night-shift EMS workers can help them keep steady blood sugar levels. Forty participants will receive a meal service and track their glucose and stress. The goal is to see if this approach is practical and worth testing in a larger t…

This study looks at whether a person's tendency to have trouble sleeping when stressed (called sleep reactivity) is a main cause of Shift Work Disorder. Researchers will reduce the mismatch between workers' body clocks and their nightshift schedule, then see if those with high sl…

This study aims to understand why night shift work is linked to obesity. Researchers will compare 1000 night shift and day workers across five European countries, measuring body composition, diet, and biological markers like hormones and inflammation. The goal is to uncover the m…