Chlamydiaceae infections

This trial tests whether a 7-day course of doxycycline can effectively cure asymptomatic anal lymphogranuloma venereum (LGV), a sexually transmitted infection caused by Chlamydia trachomatis. Currently, treatment lasts 21 days, but recent studies suggest a shorter course may work…

This study tests a new care model for veterans with opioid use disorder that combines infectious disease screening and treatment with their usual medication-assisted therapy in a single appointment. The goal is to make it easier for veterans to get tested and treated for infectio…

Researchers are testing whether sex work managers, called queen mothers, can hand out and collect HIV self-tests and self-collected STI test kits at places where female sex workers meet and work in Lusaka. The study compares this peer-supported approach with the current standard …

This trial is testing whether the GeneXpert system, a portable device that can run multiple tests, can accurately detect HIV, chlamydia, gonorrhea, hepatitis C, and HPV in community health centers and clinics. Researchers will compare its results to standard lab tests and track w…

This study will test whether a fast, point-of-care test for chlamydia and gonorrhea can reduce the time it takes for people to start antibiotics. Four hundred asymptomatic adults visiting a sexual health clinic will be randomly assigned to receive either the rapid test or a stand…

This trial tests whether teaching families to wash children's hands and faces with soap can lower the rate of active trachoma, a bacterial eye infection that can lead to blindness. About 990 children aged 1-9 in central Ethiopia will take part, with some households receiving a st…

This trial tests whether taking a single dose of the antibiotic doxycycline within 24 hours of condomless sex can prevent bacterial sexually transmitted infections (STIs) like chlamydia, gonorrhea, and syphilis in women aged 18–35 at increased risk. Participants are randomly assi…

This study explores whether providing home self-sampling kits for six sexually transmitted infections (STIs) can help sex workers get tested more easily. Participants receive a kit to collect samples at home and return them by mail, along with a questionnaire about their backgrou…

This study looks at 200 people with pneumonia to find out how many actually have an infection caused by Chlamydia pneumoniae, a type of bacteria. Researchers will use PCR tests to check for the germ and compare results with standard care. The goal is to see if this infection is o…

This study tests whether a safe dose of ivermectin, a common deworming drug, can make human feces deadly to flies that spread trachoma. Trachoma is a leading cause of blindness, and these flies carry the bacteria from person to person. Twelve healthy adults will take ivermectin, …

This study tests whether training healthcare providers to reduce stigma can increase the use of HIV and STI prevention services, like testing and preventive medications. It will involve 8 clinics in the Mississippi Delta and track changes in how often patients receive these servi…

This study looks at how satisfied young people and those with low incomes are with free HIV and STI testing and counselling in Lucerne and Zurich. Around 1,800 participants will fill out a questionnaire after their visit. The goal is to see if these free services meet people's ne…

This study looks at whether standard antibiotic doses are effective for ICU patients on ECMO (heart-lung support) or kidney dialysis. Researchers will measure drug levels in 40 adults with serious infections. The goal is to see if dosing adjustments are needed to avoid under- or …