Childhood leukemia

This study tests whether a mobile app can help children with acute lymphoblastic leukemia (ALL) keep their white blood cell counts in a healthy range during maintenance therapy. About 100 children who are already doing well on the app will be randomly assigned to continue using i…

This early-phase trial tests a drug called revumenib in people with acute leukemia who have had a stem cell transplant. The drug targets a protein that helps leukemia cells grow. The study will check safety, find the best dose, and see if it can stop the cancer from coming back. …

This study tests a new treatment called EBNK-001, made from donor immune cells (natural killer cells), in people with advanced solid tumors that have not responded to standard therapies. Participants receive the cells after chemotherapy to prepare the body, along with low-dose in…

This study tests whether coloring mandalas for 30 minutes before intrathecal chemotherapy can lower anxiety and fear in children aged 4-12 with leukemia. Sixty children will be asked to color a mandala, and their fear and anxiety levels will be measured using standard scales. The…

This study is testing whether a new tool called xDRIVE, which combines artificial intelligence and tumor profiling, can quickly suggest personalized treatment options for cancer patients in Florida whose cancer has come back or not responded to standard treatments. The goal is to…

This study is collecting genetic and drug sensitivity data from 300 children with leukemia to better understand why some cases relapse and how to target them more precisely. Researchers will analyze tumor DNA, gene activity, and test drugs on patient cells in the lab. The goal is…

This study tests whether an AI-powered chatbot can help people with blood cancers like leukemia and lymphoma better understand clinical trials and feel more willing to join them. Researchers will compare patients who get standard education plus AI chatbot sessions to those who on…