Central nervous system neoplasm
MONDO:0006130A benign or malignant, primary or metastatic neoplasm that affects the brain, meninges, or spinal cord. Representative examples of primary neoplasms include astrocytoma, oligodendroglioma, ependymoma, and meningioma. Representative examples of metastatic neoplasms include carcinoma and leukemia.
Also known as: CNS neoplasm, CNS tumor, CNS tumour, brain/spinal cord tumor, brain/spinal cord tumour, central nervous system neoplasm, central nervous system neoplasm (disease), central nervous system tumor
3348 clinical trials for this condition and its sub-types, 51 tagged with Central nervous system neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Central nervous system neoplasm
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Central nervous system cancer 130 trials · 1,699 incl. sub-types
20 sub-types
- Malignant glioma 250 trials · 915 incl. sub-types Sub-types →
- Brain cancer 680 trials · 900 incl. sub-types Sub-types →
- Primary central nervous system lymphoma 92 trials · 103 incl. sub-types Sub-types →
- Central nervous system sarcoma 2 trials · 74 incl. sub-types Sub-types →
- Spinal cord cancer 21 trials · 57 incl. sub-types Sub-types →
- Central nervous system primitive neuroectodermal neoplasm 8 trials · 24 incl. sub-types Sub-types →
- Central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor 1 trial · 22 incl. sub-types Sub-types →
- Malignant tumor of meninges 0 trials · 14 incl. sub-types Sub-types →
- Malignant adrenal gland pheochromocytoma 11 trials
- Central nervous system germinoma 2 trials · 4 incl. sub-types Sub-types →
- Central nervous system melanocytic neoplasm 1 trial · 4 incl. sub-types Sub-types →
- Central nervous system endodermal sinus tumor 0 trials · 1 incl. sub-types Sub-types →
- Choriocarcinoma of the central nervous system 0 trials Sub-types →
- Embryonal carcinoma of the central nervous system 0 trials Sub-types →
- Malignant carotid body paraganglioma 0 trials
- Malignant central nervous system mesenchymal, non-meningothelial neoplasm 0 trials Sub-types →
- Malignant jugulotympanic paraganglioma 0 trials
- Mixed germ cell tumor of central nervous system 0 trials Sub-types →
- Pheochromocytoma/paraganglioma syndrome 2 0 trials
- Pheochromocytoma/paraganglioma syndrome 5 0 trials
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Brain neoplasm 246 trials · 1,077 incl. sub-types
17 sub-types
- Brain cancer 680 trials · 900 incl. sub-types Sub-types →
- Cerebellar neoplasm 3 trials · 114 incl. sub-types Sub-types →
- Infratentorial neoplasm 6 trials · 114 incl. sub-types Sub-types →
- Brainstem neoplasm 0 trials · 101 incl. sub-types Sub-types →
- Primary brain neoplasm 87 trials · 92 incl. sub-types Sub-types →
- Hypothalamic neoplasm 3 trials · 85 incl. sub-types Sub-types →
- Pineal body neoplasm 4 trials · 22 incl. sub-types Sub-types →
- Benign neoplasm of brain 16 trials · 21 incl. sub-types Sub-types →
- Choroid plexus neoplasm 5 trials · 18 incl. sub-types Sub-types →
- Neoplasm of cerebral hemisphere 3 trials · 14 incl. sub-types Sub-types →
- Optic pathway glioma 11 trials Sub-types →
- Olfactory nerve neoplasm 0 trials · 4 incl. sub-types Sub-types →
- Cerebellopontine angle tumor 1 trial Sub-types →
- Dysembryoplastic neuroepithelial tumor 1 trial
- Childhood brain meningioma 0 trials
- Olfactory groove meningioma 0 trials
- Optic tract meningioma 0 trials Sub-types →
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Tumor of meninges 1 trial · 123 incl. sub-types
5 sub-types
- Meningioma 108 trials · 122 incl. sub-types Sub-types →
- Malignant tumor of meninges 0 trials · 14 incl. sub-types Sub-types →
- Benign neoplasm of meninges 0 trials · 5 incl. sub-types Sub-types →
- Diffuse leptomeningeal melanocytosis 0 trials
- Familial multiple meningioma 0 trials
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Central nervous system hematopoietic neoplasm 0 trials · 107 incl. sub-types
4 sub-types
- Primary central nervous system lymphoma 92 trials · 103 incl. sub-types Sub-types →
- Central nervous system leukemia 4 trials
- Intracranial cavernous angioma 0 trials
- Pituitary gland basophil adenoma 0 trials
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Spinal cord neoplasm 36 trials · 77 incl. sub-types
8 sub-types
- Spinal cord cancer 21 trials · 57 incl. sub-types Sub-types →
- Childhood spinal cord tumor 1 trial
- Benign neoplasm of spinal cord 0 trials Sub-types →
- Cervicomedullary junction neoplasm 0 trials
- Conus medullaris neoplasm 0 trials
- Neurofibroma of spinal cord 0 trials
- Spinal cord dermoid cyst 0 trials
- Spinal meningioma 0 trials
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Autonomic nervous system neoplasm 0 trials · 60 incl. sub-types
3 sub-types
- Paraganglioma 53 trials · 57 incl. sub-types Sub-types →
- Ganglioneuroma 5 trials Sub-types →
- Sympathetic neurilemmoma 0 trials
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Central nervous system organ benign neoplasm 1 trial · 57 incl. sub-types
13 sub-types
- Craniopharyngioma 29 trials Sub-types →
- Benign neoplasm of brain 16 trials · 21 incl. sub-types Sub-types →
- Benign neoplasm of meninges 0 trials · 5 incl. sub-types Sub-types →
- Central nervous system hemangioma 0 trials · 2 incl. sub-types Sub-types →
- Multinodular and vacuolating neuronal tumor 2 trials
- Diffuse leptomeningeal glioneuronal tumor 1 trial
- Polymorphous low grade neuroepithelial tumor of the young 1 trial
- Benign neoplasm of peripheral nervous system 0 trials Sub-types →
- Benign neoplasm of spinal cord 0 trials Sub-types →
- Central nervous system chondroma 0 trials
- Central nervous system leiomyoma 0 trials
- Central nervous system lipoma 0 trials Sub-types →
- Myxoid glioneuronal tumor 0 trials
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Central nervous system germ cell tumor 6 trials · 9 incl. sub-types
6 sub-types
- Central nervous system germinoma 2 trials · 4 incl. sub-types Sub-types →
- Malignant pineal area germ cell neoplasm 2 trials · 3 incl. sub-types Sub-types →
- Central nervous system nongerminomatous germ cell tumor 2 trials Sub-types →
- Childhood central nervous system germ cell tumor 0 trials · 2 incl. sub-types Sub-types →
- Adult central nervous system germ cell tumor 0 trials Sub-types →
- Mixed germ cell tumor of central nervous system 0 trials Sub-types →
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Epidural abscess 5 trials
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Optic nerve neoplasm 1 trial · 4 incl. sub-types
3 sub-types
- Optic nerve glioma 2 trials · 3 incl. sub-types Sub-types →
- Optic nerve sheath meningioma 1 trial
- Bilateral meningioma of optic nerve 0 trials
Most studied deeper sub-types
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Tumor profiling may unlock targeted drug options for pediatric cancers
Diagnosis Not yet recruitingThis study tests whether a two-step tumor profiling approach can reliably measure antibody-drug conjugate (ADC) target proteins in children and young adults with relapsed or refractory solid or central nervous system tumors. The approach uses bulk RNA sequencing to screen for tar…
Sponsor: Dana-Farber Cancer Institute • Aim: Diagnosis
Last updated Sep 02, 2026 00:00 UTC
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New program aims to make cancer surgery safer for seniors
Knowledge-focused Not yet recruitingThis study looks at how a special program, called the Geriatric Surgery Verification Program, works at the James Cancer Hospital. The program helps doctors and nurses better care for patients aged 65 and older who need cancer surgery. It includes checking for age-related issues l…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
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AI reads brain tumor types from routine slides, no special stains needed
Knowledge-focused Not yet recruitingThis study develops an artificial intelligence model that can classify brain tumors into categories, families, and specific diagnoses using only standard stained tissue slides. Researchers will train the AI on 20,000 archived images from two hospitals and test its accuracy agains…
Sponsor: Huashan Hospital • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Personalized drug test aims to outsmart refractory brain tumors
Knowledge-focused Not yet recruitingThis study tests a lab technique called pharmacoscopy that analyzes a patient's tumor tissue to find which drugs might work best for them. It includes 40 adults with various aggressive or rare brain tumors that have not responded to standard treatments. The main goal is to see if…
Phase 2 • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC