Bronchitis

This study looked at how well the antibiotic Klacid SR works for adults with respiratory infections like bronchitis and mild pneumonia, especially in those who had taken it before. Over 3,000 participants were treated in regular doctor visits, and doctors checked if symptoms impr…

This phase 3 trial tested mepolizumab, a drug that targets eosinophils (a type of white blood cell), in 18 COPD patients with eosinophilic bronchitis. The goal was to see if it reduces eosinophil levels in the airways and lowers the risk of severe flare-ups. Participants received…

This Phase 3 trial tested a new drug called YHP2401 against two other drugs for acute bronchitis. 286 adults with cough and phlegm took one of the treatments for 7 days. The goal was to see if YHP2401 works better at reducing symptoms.

This study tested two different spacer devices (valved holding chambers) used to give asthma medicine to children aged 6 months to 4 years with sudden wheezing. 80 children from Finnish hospitals took part. The goal was to see if one spacer worked better for symptom relief, hospi…

This study tested whether a herbal extract called Pelargonium sidoides (EPs®7630) helps adults with acute bronchitis recover faster and need fewer antibiotics. Over 300 participants in Switzerland were randomly assigned to receive the extract or usual care. The main goal was to s…

This completed Phase 2 trial tested whether the experimental drug ALC-2203 can reduce symptoms of acute bronchitis, like cough and chest pain. 169 adults with moderate to severe symptoms took either ALC-2203, an active comparator, or a placebo for 7 days. Researchers measured cha…

This phase 3 trial tested whether the drug N-acetylcysteine (NAC) can thin mucus and make it easier to cough up in adults with respiratory infections like bronchitis or bronchiectasis. About 333 hospitalized patients in China received either NAC, another expectorant (ambroxol), o…

This early-stage trial tests two experimental drugs, AG2203L and AG2203E, in healthy adults to see if they are safe when taken together and whether they affect each other. Participants receive each drug alone and then both together in a random order. The goal is to measure how th…

This completed study analyzed over 230,000 adults in France who had lower respiratory tract infections like pneumonia, bronchitis, or flu. Researchers used anonymous electronic health records from 2015 to 2024 to describe patient characteristics, how often antibiotics were prescr…

This completed study looked at how a special form of vitamin B3 (nicotinamide) is processed in 28 patients with low tryptophan levels due to respiratory infections or inflammatory bowel disease. Participants took either 500 mg or 1000 mg of the supplement daily for four weeks. Th…