Brain injury
MONDO:0043510Acute and chronic (see also brain INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and brain STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
Also known as: brain injury, injury of brain, brain Traumas, brain trauma
783 clinical trials for this condition and its sub-types, 220 tagged with Brain injury itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Brain injury
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Traumatic brain injury 557 trials
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Vascular brain injury 3 trials
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Eye-Tracking goggles could spot hidden brain injuries
Diagnosis Stopped earlyThis study tests whether a portable goggle system that tracks eye movements can help diagnose mild traumatic brain injury (mTBI). The goggles measure how well the eyes work together when following a specific pattern of visual cues. Researchers will compare results from people wit…
Sponsor: University of Miami • Aim: Diagnosis
Last updated Jul 26, 2026 00:00 UTC
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Music therapy brings comfort to brain injury patients
Symptom relief Stopped earlyThis study tested a music therapy program for adults with acquired brain injury, aiming to improve their comfort and well-being. Researchers worked with 27 hospitalized patients to see if group music sessions could help them feel better. The study was stopped early, so results ar…
Sponsor: University of Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Can a neck massage help your brain heal after a concussion?
Symptom relief Stopped earlyThis study looked at whether a special hand massage technique, called manual lymphatic drainage, could help clear fluid from the brain in people with moderate to severe traumatic brain injury. Only 2 people took part, and the study was stopped early. Researchers measured changes …
Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Weighted blankets may soothe agitation after brain injury
Symptom relief Stopped earlyThis study looked at whether weighted blankets can help reduce agitation and improve sleep in people recovering from a brain injury. Ten adults in a UK rehabilitation unit used the blankets for 7 days. The main goal was to see if such a study is practical in a hospital setting, n…
Sponsor: University Hospitals of Derby and Burton NHS Foundation Trust • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Robot-Assisted walking program shows promise for brain injury recovery
Symptom relief Stopped earlyThis study tested a personalized walking and balance training program using a KineAssist robotic treadmill for people recovering from traumatic brain injury, stroke, or other acquired brain injuries. The goal was to safely challenge and improve walking speed, balance, strength, a…
Sponsor: The University of Texas Medical Branch, Galveston • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Brain injury and ARDS: which breathing maneuver is safer?
Knowledge-focused Stopped earlyThis study compared two breathing techniques (CPAP and eSigh) in 18 patients with brain injury and acute respiratory distress syndrome (ARDS). The goal was to see which method better maintains oxygen levels in the brain without causing harm. The trial was terminated early, so fin…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New tool aims to measure brain injury recovery confidence
Knowledge-focused Stopped earlyThis study tested a new questionnaire called the Brain Injury Self-Efficacy Scale to see how well it measures a person's confidence in managing challenges after a brain injury. Researchers compared it with other standard self-efficacy scales. The study involved 150 adults with a …
Sponsor: Rehabilitation Hospital of Indiana • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Tiny study probes how seizure meds affect brain wiring after injury
Knowledge-focused Stopped earlyThis pilot study aimed to see if antiseizure drugs like phenobarbital and levetiracetam change brain connectivity patterns in people with severe acute brain injury and reduced consciousness. Only 5 participants were enrolled before the study was terminated. Researchers used resti…
Phase 4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC