Brain glioblastoma
MONDO:0002501A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.
Also known as: brain glioblastoma, brain glioblastoma (disease), brain glioblastoma multiforme, brain glioblastoma multiforme (disease), glioblastoma multiforme of brain, glioblastoma multiforme of the brain, grade IV astrocytic tumour of brain, grade IV brain astrocytic tumour
2976 clinical trials for this condition and its sub-types, 24 tagged with Brain glioblastoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Brain glioblastoma
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Gliosarcoma 65 trials
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Giant cell glioblastoma 7 trials
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Brain stem glioblastoma 1 trial
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Engineered immune cells take on deadly brain tumors
Disease control Stopped earlyThis early-phase study tests a new treatment for glioblastoma, an aggressive brain cancer. The approach uses a patient's own immune cells, modified in the lab to better recognize and attack the tumor, combined with chemotherapy. The main goal is to check the safety of this therap…
Phase 1 • Sponsor: Shenzhen Geno-Immune Medical Institute • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Engineered immune cells take aim at deadly brain tumors
Disease control Stopped earlyThis early-phase trial is testing a new treatment called CHM-1101 for people with a type of brain cancer (glioblastoma) that has come back or is getting worse. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack tumor cells. The …
Phase 1 • Sponsor: Chimeric Therapeutics • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Experimental virus gets a second shot at brain tumors
Disease control Stopped earlyThis study tested the safety of giving a second dose of an experimental virus (C134) directly into the brain tumor of patients whose malignant glioma had returned. Only one patient was enrolled before the study was stopped. The goal was to see if repeat dosing was safe and tolera…
Phase 1 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Could a common antifungal pill fight brain tumors?
Knowledge-focused Stopped earlyThis early-phase trial tested whether posaconazole, a drug used for fungal infections, can reach brain tumors in high enough amounts to stop cancer cells from dividing. Seven adults with glioblastoma took the drug before surgery, and researchers measured drug levels in their spin…
Early phase 1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Antifungal drug tested against brain cancer — but trial stops early
Knowledge-focused Stopped earlyThis early-phase trial tested whether ketoconazole, a drug normally used for fungal infections, can enter brain tumors in high enough amounts to stop tumor cells from dividing. Only 1 person was enrolled before the study was terminated. The goal was to measure drug levels in the …
Early phase 1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC