Bone osteosarcoma
MONDO:0002629A usually aggressive malignant bone-forming mesenchymal neoplasm arising from the bone. It may arise de novo or from a pre-existing lesion of the bone. Pain and a palpable mass are the most frequent clinical sign and symptom. It may spread to other anatomic sites, particularly the lungs.
Also known as: bone osteosarcoma, osteosarcoma of bone, osteosarcoma, somatic, osteosarcoma, somatic mutation
2794 clinical trials for this condition and its sub-types, 8 tagged with Bone osteosarcoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Bone osteosarcoma
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Conventional osteosarcoma 0 trials
4 sub-types
- Childhood intracortical osteosarcoma 0 trials
- Chondroblastic osteosarcoma 0 trials
- Fibrosarcomatous osteosarcoma 0 trials
- Osteoblastic osteosarcoma 0 trials
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Peripheral osteosarcoma 0 trials
3 sub-types
- High grade surface osteosarcoma 0 trials
- Juxtacortical osteosarcoma 0 trials Sub-types →
- Periosteal osteogenic sarcoma 0 trials
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Telangiectatic osteogenic sarcoma 0 trials
Most studied deeper sub-types
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Keyhole surgery vs. open chest: which is better for osteosarcoma lung spread?
Disease control Recruiting nowThis study compares two types of surgery to remove lung tumors that have spread from osteosarcoma (a bone cancer). One method uses a single large cut (open surgery), while the other uses several small cuts and a camera (keyhole surgery). The goal is to see which approach helps pa…
Phase 3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Lung-Directed chemo spray aims to stop cancer spread
Disease control Recruiting nowThis study tests a procedure called pulmonary suffusion, which delivers the chemotherapy drug cisplatin directly to the lungs through a minimally invasive method. The goal is to control any remaining cancer cells after surgery or ablation in patients with sarcoma or colorectal ca…
Phase 1/2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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New drug combo aims to control aggressive bone cancer in young patients
Disease control Recruiting nowThis study tests two drugs, atezolizumab and cabozantinib, in 40 adolescents and young adults (ages 12 and up) with osteosarcoma that has come back or spread. Atezolizumab helps the immune system attack cancer cells, while cabozantinib blocks enzymes that help tumors grow. The go…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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New study tests which treatment is best for pelvic bone cancers
Disease control Recruiting nowThis study compares three treatments for pelvic sarcomas (cancers in the pelvic bone): carbon ion therapy, surgery (often with radiation), and proton therapy alone. Researchers want to see which approach gives patients better quality of life and controls the cancer best. About 72…
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC