Bone fracture
MONDO:0005315Breaks in bones.
Also known as: fracture, fracture of bone, fracture(s)
867 clinical trials for this condition and its sub-types, 227 tagged with Bone fracture itself.
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Sub-types of Bone fracture
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Hip fracture 238 trials · 296 incl. sub-types
1 sub-type
- Femoral neck fracture 103 trials
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Radius fracture 89 trials
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Tibia fracture 82 trials
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Humerus fracture 65 trials
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Spinal fracture 56 trials
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Jaw fracture 47 trials
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Ulna fracture 7 trials · 8 incl. sub-types
1 sub-type
- Monteggia's fracture 1 trial
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Can a less invasive surgery speed up pilon fracture healing?
Disease control Stopped earlyThis trial compares two surgical techniques for treating pilon fractures—a serious type of ankle fracture. One method uses a minimally invasive approach with a plate, while the other uses traditional open reduction and internal fixation. The study will measure how quickly the wou…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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A common supplement may shield bones in kidney disease — a trial puts it to the test
Disease control Stopped earlyThis pilot trial investigates whether potassium citrate can improve bone quality and strength in adults and children with chronic kidney disease. Participants take either potassium citrate or a placebo for six months, along with blood and urine tests and advanced bone scans. The …
Phase 2/3 • Sponsor: Albert Einstein College of Medicine • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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New bone graft shows promise for healing leg breaks
Disease control Stopped earlyThis study tested a new bone grafting material called SurgiFill™ in 60 people with broken thigh or shin bones. The goal was to see if it helps bones heal faster and safely. The study was stopped early, so results are limited.
Sponsor: Cellontech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New shoulder implant tested for severe arthritis – but study halted early
Disease control Stopped earlyThis study looked at the TITAN Reverse Shoulder System, a device used to replace the shoulder joint in people with severe arthritis and a torn rotator cuff. The goal was to see if it relieves pain and improves movement. About 151 people were planned to take part, but the study wa…
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Blue light tested as painkiller for broken ribs
Symptom relief Stopped earlyThis study tests whether shining bright blue light on adults with painful rib fractures can reduce pain and inflammation. 75 hospitalized patients will be randomly assigned to receive blue light, white light, or standard hospital lighting for 4 hours each morning for up to 3 days…
Sponsor: Rebecca E Kotcher, MD • Aim: Symptom relief
Last updated Sep 10, 2026 00:00 UTC
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Can a simple patch replace opioids for broken ribs in seniors?
Symptom relief Stopped earlyThis trial investigates whether lidocaine patches can help older adults (65+) with rib fractures use fewer opioids while maintaining pain control. Participants receive either a lidocaine patch, a placebo patch, or standard care. The study measures opioid use and pain scores durin…
Phase 4 • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jul 10, 2026 00:00 UTC
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Real-world review of bone-fixation devices aims to confirm their safety and performance.
Knowledge-focused Stopped earlyThis study looks back at medical records of up to 118 patients in Italy who had surgery using the GALAXY FIXATION system or other Orthofix devices to stabilize fractures of the long bones (like the thigh or shin) or the pelvis. The goal is to see how well these devices hold the b…
Sponsor: Orthofix s.r.l. • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Smell test after brain surgery: what surgeons learned
Knowledge-focused Stopped earlyThis study looked at how a person's sense of smell changes after endoscopic endonasal skull base surgery, a procedure done through the nose to remove tumors or other abnormalities. Researchers measured smell using a simple identification test in 50 patients before and after surge…
Sponsor: Ricardo L. Carrau, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Ankle fracture study: does early washing protect joints?
Knowledge-focused Stopped earlyThis study looked at whether washing out the ankle joint with salt water within 48 hours of a fracture can lower inflammation and prevent cartilage breakdown. Researchers measured chemicals in the joint fluid of 41 adults before and after surgery. The goal was to see if early cle…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Bone-Lengthening nail study ends early after just one patient
Knowledge-focused Stopped earlyThis study looked at the safety and performance of the Fitbone Transport and Lengthening Nail, a device implanted in the bone to help repair large bone gaps or correct leg length differences. Only one person took part before the study was stopped early, so the results are very li…
Sponsor: Orthofix Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC