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Blue light tested as painkiller for broken ribs

NCT ID NCT06626334

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 09, 2026 · Updated 5 times

Summary

This study tests whether shining bright blue light on adults with painful rib fractures can reduce pain and inflammation. 75 hospitalized patients will be randomly assigned to receive blue light, white light, or standard hospital lighting for 4 hours each morning for up to 3 days. Researchers will measure pain levels, confusion, and blood markers of inflammation to see if blue light helps beyond usual pain treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bright blue light therapy (Carex Day-Light Classic Plus Light Therapy Lamp with blue filter)
What this could lead to
If it works, this could offer a simple, drug-free way to help manage pain and inflammation after rib fractures.
What could go wrong
This is a small, early-stage trial (75 people) testing a light-based approach that has not been proven for pain relief. The effect may be small or no different from white light or usual care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

27 people

The number who actually took part.

Started

Oct 2024

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age greater than or equal to 18 years * Admitted to a single large academic level I trauma center (Presbyterian/Montefiore hospital) within the first 48 hours of traumatic injury * Greater than or equal to 1 acute rib fracture * Pain related to rib fracture(s), by one or more of the following criteria: 1. Pain \>/= 4/10 at rest, 2. Pain \>/= 4/10 with incentive spirometer (IS) use, and/or 3. Inspiratory volume \< 1000 cc * Anticipated length of stay greater than or equal to 48 hours * Alert, with capacity to provide informed consent Exclusion Criteria: * Mechanical ventilation\* or non-invasive positive pressure ventilation administered for respiratory insufficiency prior to the time of informed consent * Delirium (positive CAM screening) at the time of informed consent * Ocular trauma, which may interfere with the mechanism of action * Traumatic brain injury (TBI) or history of TBI or stroke, which may interfere with the mechanism of action * Splenectomy upon admission or history of splenectomy, which may interfere with the mechanism of action * History of significant ocular dysfunction\*\* (i.e., macular degeneration, glaucoma, cataracts), which may interfere with the mechanism of action * History of cataract surgery, due to the possibility of blue light filtering intraocular lens placement * History of bipolar disorder or schizophrenia, which could increase the risk of an adverse reaction to light exposure (i.e., acute mania) * History of dementia, which would compromise the reliability of pain intensity and delirium measures * Or other condition in which a patient cannot open eyes to receive light intervention or report a pain score \*\*Myopia, hyperopia, and/or astigmatism corrected for with contact lenses or spectacle corrective eyeglasses will NOT be a criterion for exclusion

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia bone fracture Rib Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Presbyterian Hospital, University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.