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Smell test after brain surgery: what surgeons learned

NCT ID NCT02165969

Knowledge-focused Sponsor: Ricardo L. Carrau, MD Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how a person's sense of smell changes after endoscopic endonasal skull base surgery, a procedure done through the nose to remove tumors or other abnormalities. Researchers measured smell using a simple identification test in 50 patients before and after surgery. The goal was to find surgical methods that reduce damage to the sense of smell.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
endoscopic endonasal surgery
What this could lead to
If successful, this study could help surgeons choose techniques that better preserve a patient's sense of smell after skull base surgery.
What could go wrong
This was a small, early study that was terminated, so results are limited. The findings may not apply to all patients or surgical approaches.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

50 people

The number who actually took part.

Start date

Jun 2014

Finished

Oct 2017

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients presenting with skull base pathologies requiring endonasal surgery

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients presenting with skull base pathologies requiring endonasal surgery at The Ohio State University Wexner Medical Center * 18 years or older * Able to consent for self * Negative serum pregnancy test for women of childbearing potential Exclusion Criteria: * Patient unable to return to clinic at specific follow-up times * Pregnant or nursing * Prisoners

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Conditions

The condition(s) this trial relates to.

bone fracture neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Skull base pathology

Contacts and locations

Locations

  • The Ohio State University

    Columbus, Ohio, 43210, United States