Behcet disease

This pilot study tests whether an experimental drug called dusquetide can reduce the number and pain of mouth and genital ulcers in people with Behcet's disease, an inflammatory condition. Participants receive the drug by intravenous infusion twice a week for four weeks, with fol…

This study tested a drug called ustekinumab in 8 people with a rare, severe form of Behçet's syndrome affecting the gut, along with a blood disorder called myelodysplastic syndrome. The goal was to see if the drug could control gut symptoms and reduce disease activity over 24 wee…

This study tested the drug TA-650 (infliximab) in 18 people with Behcet's disease who had hard-to-treat lesions. The drug was given by IV every few weeks for nearly a year. The goal was to see if symptoms and signs of inflammation could be completely controlled. The trial is comp…

This study tested the drug upadacitinib in 27 adults with Behcet's syndrome that did not improve with standard treatments. The goal was to see if the drug could control symptoms like skin, eye, and blood vessel problems. Results showed that many participants had their symptoms re…

This small study tested ustekinumab, a drug that calms the immune system, in 16 adults with Behçet disease. The goal was to see if it could reduce mouth ulcers and eye inflammation. The trial is complete, but because it's early and small, we don't yet know if the drug will become…

This study looked at whether a new blood test called the pan-immune-inflammation value (PIN) can help measure disease activity in people with Behçet's syndrome. Researchers compared 80 Behçet's patients to healthy controls. The goal is to find a simple, non-invasive way to monito…

Researchers at Gazi University are studying whether Behçet's disease, which causes mouth sores and eye inflammation, is connected to gum disease. They compare 40 people with Behçet's plus gingivitis or periodontitis against 47 people with gum disease alone. The team measures infl…

This study collected blood, saliva, and eye fluid samples from 343 people with uveitis, an inflammatory eye disease that can cause vision loss. Researchers aimed to learn which genes and other factors might lead to the disease and affect treatment response. Participants were foll…

This study looked at a protein called FSTL-1 in the blood of 80 adults with Behcet's disease. The goal was to see if higher or lower levels of this protein are linked to how active the disease is. No treatments were tested; the study only measured and compared protein levels with…

This study examined anxiety, depression, fatigue, and quality of life in 20 adults with Behçet's disease using questionnaires. Researchers aimed to understand the psychological symptoms that often accompany this rare inflammatory condition. The study was observational and did not…