Bacterial vaginosis
MONDO:0005316Infection caused by bacterial overgrowth in the vagina. Most affected women are asymptomatic. When symptoms occur, they include foul-smelling vaginal discharge, vaginal itching, and burning. Risk factors include sexual activity with multiple partners and the use of vaginal douches and intrauterine devices. Up to a third of cases resolve without treatment. Antibiotic treatment is recommended when symptoms are present and for women that are pregnant at the time of infection.
Also known as: BV
44 clinical trials for this condition and its sub-types, 44 tagged with Bacterial vaginosis itself.
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Could donor bacteria beat recurring vaginal infections?
Disease control OngoingThis trial tests whether transferring vaginal fluid from healthy donors can help people with recurrent bacterial vaginosis (BV) that doesn't respond well to antibiotics. Participants receive either the donor fluid or a placebo (saline) to see if the transplant restores a healthie…
Phase 1/2 • Sponsor: Hadassah Medical Organization • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Could a 'Flora Transplant' stop recurring vaginal infections?
Disease control OngoingThis study tests whether transferring healthy vaginal bacteria from donors can cure recurrent bacterial vaginosis (BV). Ten women with frequent BV will receive the transplant. The goal is to restore natural balance and prevent repeat infections without antibiotics.
Sponsor: Hadassah Medical Organization • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Study to prevent preterm birth by frequent vaginal infection screening abandoned
Prevention CancelledThis study aimed to find out if checking pregnant women for bacterial vaginosis every two weeks could reduce the chance of early delivery. It planned to include women with a history of preterm birth. However, the trial was withdrawn before any participants were enrolled, so no re…
Sponsor: Loma Linda University • Aim: Prevention
Last updated Jun 26, 2026 16:46 UTC
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New natural gel for bacterial vaginosis passes first safety check
Symptom relief OngoingThis early-stage study tests whether LCFA-01, a natural gel containing oleic acid, is safe and comfortable when placed in the vagina. Thirty healthy women aged 18-40 will use the gel and be monitored for side effects, discomfort, and how much of the product enters the bloodstream…
Phase 1 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
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Quick STI tests may slash unneeded antibiotics for vaginal discharge
Knowledge-focused OngoingThis study in Nepal tests whether using rapid point-of-care tests for sexually transmitted infections can reduce the overuse of antibiotics for vaginal discharge. About 1,500 women will be split into three groups: standard care, test-guided treatment, or test-guided treatment plu…
Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC