Autoimmune hepatitis
MONDO:0016264Hepatitis caused by autoantibodies. Drugs, infections, and toxins may trigger the production of the autoantibodies against the liver parenchyma.
Also known as: autoimmune liver disease, autoimmune hepatitis, autoimmune chronic active hepatitis, autoimmune hepatitis with centrilobular necrosis, chronic autoimmune hepatitis, AIH, autoimmune chronic hepatitis
66 clinical trials for this condition and its sub-types, 30 tagged with Autoimmune hepatitis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Autoimmune hepatitis
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Autoimmune cholangitis 1 trial
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Autoimmune hepatitis type 1 0 trials
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Autoimmune hepatitis type 2 0 trials
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Autoimmune hepatitis type 3 0 trials
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Seronegative autoimmune hepatitis 0 trials
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New drug aims to tame autoimmune hepatitis and cut steroid use
Disease control Not yet recruitingThis study tests a drug called inebilizumab in 180 adults with autoimmune hepatitis, a condition where the immune system attacks the liver. The goal is to see if the drug can reduce liver inflammation and allow patients to take lower doses of steroids. Participants will receive e…
Phase 3 • Sponsor: Amgen • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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New hope for immunotherapy side effects: blood filtering may replace steroids
Disease control Not yet recruitingThis study tests a treatment called extracorporeal photopheresis (ECP) for people with advanced melanoma who develop severe colitis or hepatitis from immunotherapy. ECP filters a patient's blood, treats it with a light-activated drug, and returns it to the body. The trial compare…
Phase 2 • Sponsor: Therakos LLC • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New mRNA shot aims to calm stubborn autoimmune diseases
Disease control Not yet recruitingThis early-phase study tests a new drug called WGb-0301 for people with autoimmune diseases (like lupus or autoimmune hepatitis) that haven't responded to standard treatments. The drug uses mRNA technology to target and clear certain immune cells (B cells) that are causing the di…
Early phase 1 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Two autoimmune conditions, one child: study probes hidden thyroid trouble
Knowledge-focused Not yet recruitingAutoimmune hepatitis makes a child's immune system attack their liver. Researchers at Assiut University Children's Hospital want to know how many children with this liver condition also develop thyroid disorders such as Hashimoto thyroiditis or Graves' disease. The team will test…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Blood fats and nanoparticles may reveal hidden clues in autoimmune liver disease
Knowledge-focused Not yet recruitingThis study looks at two types of liver disease — autoimmune hepatitis and non-alcoholic fatty liver disease — to see if fats in blood cells and tiny particles called extracellular vesicles differ between them. Researchers will collect blood samples from 24 adults and analyze thes…
Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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800-Patient study aims to unlock secrets of autoimmune liver disease
Knowledge-focused Not yet recruitingThis French study will collect medical data and biological samples from 800 people with autoimmune liver diseases. Researchers hope to identify new markers that explain why some patients respond well to treatment while others do not. The goal is to better understand the immune me…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC