Arteriosclerosis obliterans
MONDO:0006659Common occlusive arterial disease which is caused by atherosclerosis. It is characterized by lesions in the innermost layer (arterial intima) of arteries including the aorta and its branches to the extremities. Risk factors include smoking, hyperlipidemia, and hypertension.
Also known as: arteriosclerosis obliterans (disorder) [ambiguous]
99 clinical trials for this condition and its sub-types, 14 tagged with Arteriosclerosis obliterans itself.
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Which leg artery fix works best? trial puts bypass, stents, and balloons head to head
Disease control Recruiting nowResearchers at one hospital are observing 400 people with arteriosclerosis obliterans, a condition where plaque blocks arteries in the legs. The study compares four common procedures: bypass surgery, bare metal stents, plain balloon angioplasty, and drug-coated balloons. Over thr…
Sponsor: First Affiliated Hospital, Sun Yat-Sen University • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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New stent study aims to keep blood flowing in blocked aortic arteries
Disease control Recruiting nowThis study looks at how safe and effective a special stent (VBX) is for treating blocked arteries near the aorta in the lower belly. About 158 people who already had this stent placed at least a year ago will be followed. The goal is to see if the artery stays open and if there a…
Sponsor: W.L.Gore & Associates • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New stent aims to keep leg arteries open longer
Disease control Recruiting nowThis study tests whether a fabric-covered stent (GORE VBX) works better than standard bare metal stents for people with severe blockages in the iliac arteries, which supply blood to the legs. About 244 participants with leg pain or tissue loss will be randomly assigned to receive…
Sponsor: W.L.Gore & Associates • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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BeatMove device: could music be the key to better walking rehab?
Symptom relief Recruiting nowThis study tests whether music therapy delivered by the BeatMove device can help people with leg artery disease walk farther during a 3-month outpatient walking program. Fifty-four participants will either get real music therapy or a sham version while doing 36 walking sessions. …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Single shot vs. catheter: which pain block is better for belly surgery?
Symptom relief Recruiting nowThis study compares two methods of pain control for people having open abdominal surgery. One group gets a single injection of a long-lasting numbing medicine into the belly muscles during surgery. The other group gets a standard numbing medicine through small tubes placed in the…
Phase 4 • Sponsor: Hartford Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 12:40 UTC
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New device tracks blood flow in leg artery patients
Knowledge-focused Recruiting nowThis study tests a non-invasive device that measures blood flow in the skin of people with severe leg artery disease. Researchers will compare results from 15 patients before and after a procedure to open blocked arteries, and also compare them to 15 healthy volunteers. The goal …
Sponsor: ODI Medical AS • Aim: Knowledge-focused
Last updated Aug 27, 2026 00:00 UTC
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Can frailty predict stent failure? new study investigates
Knowledge-focused Recruiting nowThis study tracks 98 people with peripheral artery disease who had a stent placed in their iliac artery. Researchers want to see which patients later develop serious limb complications, like needing another procedure or amputation. They will also check if frailty plays a role. Th…
Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC