Apraxia
MONDO:0000665Apraxia is a neurological disorder characterized by the inability to perform tasks or movements, despite having the desire and physical ability to perform them. It is caused by damage to the brain, especially the parietal lobe, and can arise from many diseases, tumors, a stroke, or traumatic brain injury. In some cases it is present from birth. There are several types of apraxia, which may occur alone or together. These include: Buccofacial or orofacial apraxia is the inability to carry out facial movements on demand. This may include licking the lips, sticking out the tongue, whistling, coughing, or winking. Ideational apraxia is the inability to carryout learned, complex tasks with multiple, sequential movements. This may include dressing, eating, and bathing. Ideomotor apraxia is the inability to perform a learned task (such as using a tool) or communicate using gestures (like waving good-bye). Limb-kinetic apraxia is the inability to make fine, precise movements with an arm or leg. This may include buttoning a shirt or tying a shoe. Verbal apraxia is difficulty coordinating mouth and speech movements. Verbal apraxia may be acquired or present from birth. Constructional apraxia is the inability to copy, draw, or construct simple figures. Oculomotor apraxia is difficulty moving the eyes on command. Treatment of apraxia may include physical, speech, or occupational therapy. If apraxia occurs as a symptom of another disorder, treatment should be directed to the underlying condition.
Also known as: Apraxias, dyspraxia
40 clinical trials for this condition and its sub-types, 17 tagged with Apraxia itself.
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Sub-types of Apraxia
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Gait apraxia 23 trials
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Ideomotor apraxia 0 trials
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Cord blood hope: new infusion option for kids with brain damage
Disease control Expanded accessThis program gives children with brain disorders like cerebral palsy or stroke access to umbilical cord blood infusions. The treatment uses donated cord blood cells to help repair brain damage. Kids up to age 26 with normal immune function may qualify. The goal is to improve symp…
Sponsor: Joanne Kurtzberg, MD • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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New therapy aims to help kids with speech disorder speak in phrases
Symptom relief Recruiting nowThis study tests a speech therapy called DTTC-Connect for children aged 3 to 12 with childhood apraxia of speech, a disorder that makes it hard to say words clearly. The therapy focuses on helping children move from saying single words to speaking in phrases. Sixty-eight children…
Sponsor: New York University • Aim: Symptom relief
Last updated Sep 20, 2026 00:00 UTC
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Can intensive speech therapy rewire speech in children with rare genetic conditions?
Symptom relief Recruiting nowResearchers are testing whether four weeks of intensive motor speech therapy can improve speech accuracy in children who have childhood apraxia of speech along with a rare genetic condition. The study enrolls up to 20 children aged 3 to 16. Each child receives 12 sessions of eith…
Sponsor: Murdoch Childrens Research Institute • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
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Bilingual brain boost: new therapy targets language loss in dementia
Symptom relief Recruiting nowThis study tests a speech therapy program for bilingual Spanish-English or Spanish-Catalan speakers with primary progressive aphasia, a condition that slowly damages language abilities. Sixty participants will receive personalized script training via video sessions, while 30 othe…
Sponsor: Stephanie Grasso • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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Could a tiny zap to the head help stroke survivors speak again?
Symptom relief Recruiting nowThis study tests whether a safe, mild electrical current applied to the scalp (tDCS) can make speech therapy work better for people who have trouble speaking after a stroke. 24 participants with apraxia of speech will receive both real and sham stimulation at different times to s…
Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New speech therapy aims to help nonverbal kids with autism find their voice
Symptom relief Recruiting nowThis study tests a special speech therapy for minimally verbal children who have both autism and childhood apraxia of speech (a motor planning disorder). The therapy uses motor learning principles in a natural play-like setting. Researchers will enroll 20 children to see if this …
Sponsor: MGH Institute of Health Professions • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Brain scans and speech tests could unlock mystery of rare speech disorder
Knowledge-focused Recruiting nowThis study at Mayo Clinic looks at two different types of Progressive Apraxia of Speech, a condition that makes it hard to speak clearly. Researchers will use brain scans, speech assessments, and thinking tests in 47 adults to better tell these types apart. The goal is to improve…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New brain scan study aims to unravel mysteries of speech disorder
Knowledge-focused Recruiting nowThis study uses advanced brain scans, including a special PET tracer called AV-1451, to track changes in the brains of 50 people with progressive apraxia of speech (a disorder that affects the ability to coordinate speech movements). Researchers at Mayo Clinic will compare these …
Phase 4 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC