Ankle injury
MONDO:0043895Harm or hurt to the ankle or ankle joint usually inflicted by an external source.
Also known as: ankle injury, injury of ankle, injury of tarsal region, tarsal region injury, Injuries, ankle, Injuries, syndesmotic, Sprains, ankle, ankle Sprains
173 clinical trials for this condition and its sub-types, 81 tagged with Ankle injury itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
-
Dissolving screws could spare ankle fracture patients a second surgery
Disease control Not yet recruitingThis study tests a new type of screw made from a magnesium alloy that slowly dissolves in the body over two to three years. Unlike standard metal screws, these biodegradable screws may not need to be removed in a second surgery. The trial enrolls adults aged 18 to 80 with unstabl…
Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
-
New flap surgery aims to heal tough leg and foot wounds
Disease control Not yet recruitingThis study tests a surgical technique to cover deep wounds on the lower leg, ankle, heel, or foot. The procedure moves skin and tissue from the outer lower leg to the wound area, using a special blood supply to help it heal. The study will include 30 adults and will measure how w…
Sponsor: Assiut University • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
-
Handheld ankle scanner could revolutionize sprain diagnosis
Diagnosis Not yet recruitingThis study will test a new portable device called the Cobra Ankle Arthrometer to see if it can accurately measure ankle joint looseness. Researchers will compare it to ultrasound imaging in 62 young adults, including those with chronic ankle instability, previous sprains, or no a…
Sponsor: University of Virginia • Aim: Diagnosis
Last updated Jun 26, 2026 15:15 UTC
-
New surgical approach aims to improve ankle fracture recovery
Symptom relief Not yet recruitingResearchers compare two surgical methods for complex ankle fractures that also involve a tear of the ligament connecting the two lower leg bones. Adults aged 18 to 55 with these injuries receive either dynamic fixation or standard screw fixation. The trial tracks ankle function a…
Sponsor: Fuzhou University Affiliated Provincial Hospital • Aim: Symptom relief
Last updated Sep 21, 2026 17:00 UTC
-
Can passing strength tests beat the calendar for safer return to football?
Symptom relief Not yet recruitingResearchers compare two ways to guide football players back from ACL reconstruction, hamstring strain, or ankle sprain. One program lets players advance only when they pass hop, balance, and readiness tests; the other moves them forward on a set timeline. Both groups do six weeks…
Sponsor: Riphah International University • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
-
Pedal bike study aims to speed leg injury recovery
Symptom relief Not yet recruitingThis study tests if using a floor pedal bike at home helps people recover from leg fractures and ankle injuries. Twenty adults with these injuries will get a bike at their first post-surgery visit and be asked to use it regularly. Researchers will track their physical activity an…
Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Aug 27, 2026 00:00 UTC
-
New ankle brace could help people with chronic instability
Symptom relief Not yet recruitingThis study tests a new ankle orthosis (brace) in 4 people with chronic ankle injuries or nerve damage that limits ankle movement. Participants will wear the new brace for one month and compare it to their usual brace or no brace. The goal is to see if the new device improves ankl…
Sponsor: University of Salamanca • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
-
Which anesthesia gets you home faster after ankle surgery?
Symptom relief Not yet recruitingThis study will compare three types of anesthesia for people having ankle surgery: total intravenous anesthesia with a nerve block, general anesthesia with a nerve block, and spinal anesthesia. The goal is to see which method allows patients to recover and leave the hospital the …
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
-
Can pressurized oxygen heal sprained ankles faster?
Symptom relief Not yet recruitingThis study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help people with acute ankle sprains heal better and faster. Researchers will enroll 208 people with recent ankle sprains and compare those who get hyperbaric oxygen to those w…
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
-
Could a simple solution replace the tourniquet in ankle surgery?
Symptom relief Not yet recruitingThis study compares two methods to keep the surgical area clear during ankle arthroscopy: using a dilute epinephrine solution versus a traditional tourniquet. About 88 people with chronic ankle instability or ligament injuries will be randomly assigned to one method. The goal is …
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
-
Hip exercises may beat ankle workouts for wobbly ankles in athletes
Symptom relief Not yet recruitingThis study tests whether focusing on hip muscles or ankle muscles during exercise training better improves leg function in athletes with chronic ankle instability. 36 professional athletes will do a 6-week program targeting either the gluteus medius, gluteus maximus, or ankle mus…
Sponsor: Hacettepe University • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
-
Could a needle beat a brace for ankle sprains?
Symptom relief Not yet recruitingThis study tests a new type of acupuncture called Fu's subcutaneous needling against the usual treatment of wearing a brace and doing exercises for people with recent ankle sprains. The goal is to see which approach better reduces pain, improves ankle function, and prevents the s…
Sponsor: Guangzhou University of Chinese Medicine • Aim: Symptom relief
Last updated Jun 26, 2026 18:43 UTC
-
Could a fluid from stem cells ease knee pain without surgery?
Symptom relief Not yet recruitingThis early-phase trial tests whether injecting a fluid made from stem cells (called secretome) mixed with growth factors from the patient's own blood can safely reduce knee pain and improve function in people with mild knee osteoarthritis. The study will enroll 25 adults aged 30-…
Early phase 1 • Sponsor: University of the Punjab • Aim: Symptom relief
Last updated Jun 26, 2026 13:45 UTC
-
New program aims to cut delays in knee surgery for hispanic youth athletes
Knowledge-focused Not yet recruitingThis study tests a program to help Hispanic teen soccer players get timely knee surgery. Many face barriers like language and insurance issues that delay care. The program includes an educational talk and a bilingual navigator to guide families. The goal is to see if this approac…
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
-
Could your pelvis be the key to preventing ankle sprains?
Knowledge-focused Not yet recruitingThis study looks at whether pelvic alignment differs between male athletes with and without chronic ankle instability. Researchers will measure ankle stability, balance, and pelvic angles in 38 football players. The goal is to better understand how the pelvis and ankle work toget…
Sponsor: Ahmed Korany Abdallah Ahmed • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
-
Ankle vs. knee: which injury wobbles you more?
Knowledge-focused Not yet recruitingThis study looks at how two common leg injuries—ankle sprains and kneecap pain—affect balance in different directions. Researchers will measure stability in 90 people using a special balance machine. The goal is to find out if each injury causes a unique type of balance problem, …
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
-
Can a phone app replace the Doctor's exam for ankle recovery?
Knowledge-focused Not yet recruitingThis study checks if a smartphone app can reliably measure calf muscle strength in people recovering from Achilles tendon rupture or ankle sprain. Researchers will compare results from 70 participants (patients and healthy controls) using the app during calf raise exercises. The …
Sponsor: Schulthess Klinik • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC