Angioedema
MONDO:0010481Swelling involving the deep dermis, subcutaneous, or submucosal tissues, representing localized edema. Angioedema often occurs in the face, lips, tongue, and larynx.
Also known as: Edemas, angioneurotic, Quincke edema, Quincke oedema, Quincke's edema, Quincke's oedema, Quinckes edema, Quinckes oedema, Urticarias, giant
67 clinical trials for this condition and its sub-types, 19 tagged with Angioedema itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Angioedema
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Hereditary angioedema 58 trials · 60 incl. sub-types
10 sub-types
- Hereditary angioedema with C1Inh deficiency 14 trials · 32 incl. sub-types Sub-types →
- Hereditary angioedema type 3 2 trials
- Hereditary angioedema with normal C1Inh 2 trials
- PLG-related hereditary angioedema with normal C1inh 0 trials
- Angioedema, hereditary, 4 0 trials
- Angioedema, hereditary, 5 0 trials
- Angioedema, hereditary, 6 0 trials
- Angioedema, hereditary, 7 0 trials
- Angioedema, hereditary, 8 0 trials
- Hereditary angioedema with normal C1inh not related to F12 or PLG variant 0 trials
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Acquired angioedema 2 trials · 3 incl. sub-types
5 sub-types
- Renin-angiotensin-aldosterone system-blocker-induced angioedema 2 trials
- Acquired angioedema with C1Inh deficiency 1 trial
- Acquired angioedema type 1 0 trials
- Acquired angioedema type 2 0 trials
- Vibratory angioedema 0 trials
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Non-histaminic angioedema 2 trials
Most studied deeper sub-types
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Could a daily pill stop hereditary angioedema attacks?
Disease control Stopped earlyThis trial tests whether an experimental oral medication, deucrictibant, can reduce the number of swelling attacks in people with hereditary angioedema (HAE) types I and II. Participants take either a low or high dose of the drug or a placebo for 12 weeks, and then may continue o…
Phase 2 • Sponsor: Pharvaris Netherlands B.V. • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New daily pill aims to stop HAE attacks, but trial cut short
Disease control Stopped earlyThis phase 2 trial tested KVD824, an oral pill, to prevent swelling attacks in people with hereditary angioedema types I and II. The study planned to compare three doses against a placebo over several months. However, the trial was terminated early with only 33 participants, so t…
Phase 2 • Sponsor: KalVista Pharmaceuticals, Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Scientists hunt for blood clues to tame unpredictable swelling attacks
Knowledge-focused Stopped earlyThis study aimed to find biomarkers (measurable substances in the blood) that could help doctors diagnose bradykinin angioedema and predict how severe attacks might be. The condition causes sudden, unpredictable swelling, and current tests don't work well for all types. Researche…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC