Alzheimer disease 2
MONDO:0007089An Alzheimer's disease that is characterized by an association of the apolipoprotein E E4 allele.
Also known as: AD2, Alzheimer disease 2, Alzheimer disease associated with APOE E4, Alzheimer disease associated with APOE4, Alzheimer disease type 2, Alzheimer's disease 2, Alzheimer's disease type 2, late onset Alzheimer disease
14 clinical trials for this condition and its sub-types, 11 tagged with Alzheimer disease 2 itself.
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Could flickering lights and tones help fight Alzheimer's? major trial underway
Disease control CompletedThis study tests a device that delivers specific light and sound patterns to the brain, aiming to slow the progression of mild-to-moderate Alzheimer's disease. About 670 participants will use the device at home for an hour daily over a year, with half receiving a sham (inactive) …
Sponsor: Cognito Therapeutics, Inc. • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Simple blood test could spot Alzheimer's early
Diagnosis CompletedThis study is working on a blood test to help diagnose Alzheimer's disease. Researchers are measuring two specific markers in the blood of 200 people—some with Alzheimer's and some healthy—to see if these markers can reliably tell the difference. The goal is to create a simple, n…
Sponsor: Amoneta Diagnostics SAS • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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R2D2 trial: deprescribing anticholinergics may shield aging brains
Prevention CompletedThis study tests whether a pharmacist-led program to stop certain medications (anticholinergics) can lower dementia risk in older adults. 344 participants aged 65+ who take these drugs will be followed for 2 years, comparing cognitive changes and quality of life between those who…
Sponsor: Indiana University • Aim: Prevention
Last updated Aug 05, 2026 00:00 UTC
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Music as medicine: personalized tunes may boost brain function in Late-Stage Alzheimer's
Symptom relief CompletedThis study tested whether listening to personalized music can improve thinking and daily function in people with advanced-stage Alzheimer's disease. Researchers enrolled 54 older adults and had them listen to either their favorite music or a classical piece. The goal was to see i…
Sponsor: Okan University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Sleep hack may slow Alzheimer's: early study tests Time-in-Bed restriction
Knowledge-focused CompletedThis study tests whether spending less time in bed for four weeks can deepen sleep and boost memory in adults aged 65-85 who have poor sleep and are at risk for Alzheimer's. Researchers will measure brain activity, memory, and blood markers. The goal is to see if a simple behavio…
Early phase 1 • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Planning ahead: study tests if care wishes are honored
Knowledge-focused CompletedThis study looked at whether a special planning tool, called a POST form, helps older adults (65+) get the medical care they prefer at the end of life. Researchers worked with 389 people, including those with dementia, to see if their treatment matched their wishes. The goal was …
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC